Neurophysiology and Sleep Physiology Research Sepulveda Center, Veterans Administration, Greater Los Angeles Healthcare System and Departments of Psychology and Medicine, University of California at Los Angeles 16111 Plummer St., Sepulveda, California 91343, USA
dmcginty@ucla.edu
A 70-year-old hypothesis that a rostral hypothalamic area is essential for maintaining sleep is re-awakened by the demonstration that the sleep-active ventrolateral preoptic neurons interact with wake-promoting systems in the upper brainstem.