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Nature Medicine  6, 383 - 385 (2000)
doi:10.1038/74641

Neuroprotective autoimmunity—a double-edged sword?

Matthew J.A. Wood1 & Angela Vincent2

1  Department of Human Anatomy and Genetics, Oxford University, OX1 3QX, UK

2  Neurosciences Group Department of Clinical Neurology Institute of Molecular Medicine John Radcliffe Hospital Oxford University, OX3 9DU, UK
AVincent@hammer.imm.ox.ac.uk

Glutamate receptors are thought to play an essential role in the central nervous system damage that results from certain neurological insults. A recent report indicates that immunization against a glutamate receptor subunit may have neuroprotective effects, but we must consider the potential for pathogenic autoimmune responses.

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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