'New variant' Creutzfeldt-Jakob disease and bovine spongiform encephalopathy
Moira E. Bruce
Institute for Animal Health Neuropathogenesis Unit Ogston Building West Mains Road Edinburgh EH9 3JF, UK. moira.bruce@bbsrc.ac.uk
The discovery of 'new variant' Creutzfeldt-Jakob disease (vCJD) was announced in March 1996. By mid-1997, several lines of evidence linked vCJD with bovine spongiform encephalopathy (BSE), the most compelling being that BSE and vCJD produced an identical disease in conventional mice. Recent studies in transgenic mice support this conclusion.
