The Seattle VA Medical Center, Department of Medicine,
University of Washington, Seattle, Washington
98108, USA
trmartin@u.washington.edu
The individual searches for a natural antagonist of cortisol and for critical
mediators of sepsis have converged in the finding that MIF is an important
mediator of septic shock. The intersection of these two efforts reminds us
that progress in scientific research often comes from surprising directions
(164−170).