Department of Medicine, 0682 University of California, San Diego 9500 Gilman Drive, MTF 110 La Jolla, California 92093-0682
wpalinski@ucsd.edu
Statins reduce the expression of the class II major histocompatibility complex (MHCII) by arterial cells, leading to a decreased T-cell response. This indicates that statins may be useful in treating graft atherosclerosis and other chronic inflammatory conditions. (pages 1399−1402)