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Clinical Trials and Tribulations p1193
doi:10.1038/81249
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| Letters to Editor | Top |
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The Quest Trial, a paradigm of HIV collaborative research p1194
Li-Ean Goh, Hugh McDade, Sabine Kinloch, Luc Perrin, David Cooper, Andrew Phillips, Bruno Hoen, Brigitte Autran, Anders Sonnerborg
& Chris Tsoukas
doi:10.1038/81251
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(61K)
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| News | Top |
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Merger signals shift in xenotransplantation research p1195
Karen Birmingham
doi:10.1038/81253
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(106K)
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Skepticism surrounds triple Nobel winners p1196
Kristine Novak
doi:10.1038/81256
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(141K)
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Abortion drug approval opens up research p1196
Marlene Cimons
doi:10.1038/81261
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(141K)
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USDA gives ground over lab animals p1197
Alan Dove
doi:10.1038/81263
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(78K)
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NIH gives money for orphan development pp1197 - 1198
Myrna E. Watanabe
doi:10.1038/81266
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(105K)
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Placebo trials deemed unethical p1198
Tinker Ready
doi:10.1038/81268
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Brazilian studies supported long-term p1198
Xavier Bosch
doi:10.1038/81271
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UK insurers allowed to use genetic tests p1199
David Dickson
doi:10.1038/81274
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(114K)
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South African village prepares for first HIV vaccine trial . . . pp1199 - 1200
Harold Connett
doi:10.1038/81276
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(214K)
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. . .while government causes confusion p1200
Karen Birmingham
doi:10.1038/81280
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(153K)
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| Commentary | Top |
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The National Institutes of Health and clinical research: a progress report pp1201 - 1204
David G. Nathan
& Harold E. Varmus
doi:10.1038/81282
Abstract | Full text | PDF
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| Book Reviews | Top |
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Ethical Issues in Biomedical Publication p1205
Reviewed by: Adrian J. Ivinson
doi:10.1038/81285
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(99K)
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The Triple Helix: Gene, Organism and Environment p1206
Reviewed by: Deborah M. Gordon
doi:10.1038/81288
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(125K)
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| News and Views | Top |
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Parkinson disease gene therapy moves toward the clinic pp1207 - 1208
Anders Björklund
& Olle Lindvall
doi:10.1038/81291
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Normal and mutant huntingtin: Partners in crime? pp1208 - 1209
Nicholas A. Di Prospero
& Danilo A. Tagle
doi:10.1038/81294
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To be or notch to be pp1210 - 1211
Malcolm Brenner
doi:10.1038/81297
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(1,016K)
See also: Article by Varnum-Finney et al. |
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Seeing is believing p1211
Kristine Novak
doi:10.1038/81300
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(998K)
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Stem cell alchemy pp1212 - 1213
Stuart H. Orkin
doi:10.1038/81303
Abstract | Full text | PDF
(89K)
See also: Article by Lagasse et al. |
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Split stories converge at desmoglein 1. pp1213 - 1214
Ervin Epstein Jr.
doi:10.1038/81306
Abstract | Full text | PDF
(112K)
See also: Article by Amagai et al. |
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Meningococcal genomics: two steps forward, one step back. pp1215 - 1216
Martin C. Maiden
& Ian M. Feavers
doi:10.1038/81309
Abstract | Full text | PDF
(139K)
See also: Article by Sun et al. |
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Not a minute to waste pp1216 - 1217
George E.O. Muscat
& Uwe Dressel
doi:10.1038/81312
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Malaria vaccines−targeting infected hepatocytes pp1218 - 1219
Stephen L. Hoffman
& Denise L. Doolan
doi:10.1038/81315
Abstract | Full text | PDF
(96K)
See also: Article by Daubersies et al. |
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Research News p1220
Kristine Novak, John MacFarlane
& Sandra Aamodt
doi:10.1038/81318
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| Review | Top |
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Decoding calcium signals involved in cardiac growth and function pp1221 - 1227
Norbert Frey, Timothy A. McKinsey
& Eric N. Olson
doi:10.1038/81321
Abstract | Full text | PDF
(231K)
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| Articles | Top |
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Purified hematopoietic stem cells can differentiate into hepatocytes
in vivo pp1229 - 1234
Eric Lagasse, Heather Connors, Muhsen Al-Dhalimy, Michael Reitsma, Monika Dohse, Linda Osborne, Xin Wang, Milton Finegold, Irving L. Weissman
& Markus Grompe
doi:10.1038/81326
Abstract | Full text | PDF
(631K)
See also: News and Views by Orkin |
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Stem cell repopulation efficiency but not pool size is governed by p27kip1 pp1235 - 1240
Tao Cheng, Neil Rodrigues, David Dombkowski, Sebastian Stier
& David T. Scadden
doi:10.1038/81335
Abstract | Full text | PDF
(128K)
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Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation pp1241 - 1247
Timothy S. Zheng, Stéphane Hunot, Keisuke Kuida, Takashi Momoi, Anu Srinivasan, Donald W. Nicholson, Yuri Lazebnik
& Richard A. Flavell
doi:10.1038/81343
Abstract | Full text | PDF
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A peptide−doxorubicin 'prodrug' activated by prostate-specific antigen selectively kills prostate tumor cells positive for prostate-specific antigen in vivo pp1248 - 1252
Deborah DeFeo-Jones, Victor M. Garsky, Bradley K. Wong, Dong-Mei Feng, Trina Bolyar, Kathleen Haskell, David M. Kiefer, Karen Leander, Elizabeth McAvoy, Patricia Lumma, Jenny Wai, Edith T. Senderak, Sherri L. Motzel, Kevin Keenan, Matthew Van Zwieten, Jiunn H. Lin, Roger Freidinger, Joel Huff, Allen Oliff
& Raymond E. Jones
doi:10.1038/81351
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Conjugation of arginine oligomers to cyclosporin A facilitates topical
delivery and inhibition of inflammation pp1253 - 1257
Jonathan B. Rothbard, Sarah Garlington, Qun Lin, Thorsten Kirschberg, Erik Kreider, P. Leo McGrane, Paul A. Wender
& Paul A. Khavari
doi:10.1038/81359
Abstract | Full text | PDF
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Protection against Plasmodium falciparum malaria in chimpanzees
by immunization with the conserved pre-erythrocytic liver-stage antigen 3
pp1258 - 1263
Pierre Daubersies, Alan W. Thomas, Pascal Millet, Karima Brahimi, Jan A.M. Langermans, Benjamin Ollomo, Lbachir BenMohamed, Bas Slierendregt, Wijnand Eling, Alex Van Belkum, Guy Dubreuil, Jacques F.G.M. Meis, Claudine Guérin-Marchand, Sylvie Cayphas, Joe Cohen, Hélène Gras-Masse
& Pierre Druilhe
doi:10.1038/81366
Abstract | Full text | PDF
(286K)
See also: News and Views by Hoffman & Doolan |
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Cytoadhesion of Plasmodium falciparum ring-stage-infected erythrocytes
pp1264 - 1268
B. Pouvelle, P.A. Buffet, C. Lépolard, A. Scherf
& J. Gysin
doi:10.1038/81374
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Functional genomics of Neisseria meningitidis pathogenesis pp1269 - 1273
Yao-Hui Sun, Sharmila Bakshi, Ronald Chalmers
& Christoph M. Tang
doi:10.1038/81380
Abstract | Full text | PDF
(138K)
See also: News and Views by Maiden & Feavers |
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Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets
desmoglein 1 pp1275 - 1277
M. Amagai, N. Matsuyoshi, Z. H. Wang, C. Andl
& J. R. Stanley
doi:10.1038/81385
Abstract | Full text | PDF
(299K)
See also: News and Views by Epstein |
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Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized
by constitutive Notch1 signaling pp1278 - 1281
Barbara Varnum-Finney, Lanwei Xu, Carolyn Brashem-Stein, Cynthia Nourigat, David Flowers, Sonia Bakkour, Warren S. Pear
& Irwin D. Bernstein
doi:10.1038/81390
Abstract | Full text | PDF
(232K)
See also: News and Views by Brenner |
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Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep pp1282 - 1286
Kenneth W. Liechty, Tippi C. MacKenzie, Aimen F. Shaaban, Antoneta Radu, AnneMarie B. Moseley, Robert Deans, Daniel R. Marshak
& Alan W. Flake
doi:10.1038/81395
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| New Technology | Top |
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A new approach for analyzing proton magnetic resonance spectroscopic images of brain tumors: nosologic images pp1287 - 1289
Fabien Szabo De Edelenyi, Christophe Rubin, François Estève, Sylvie Grand, Michel Décorps, Virgine Lefournier, Jean-François Le Bas
& Chantal Rémy
doi:10.1038/81401
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Human immunodeficiency virus type 1 reverse transcriptase and protease mutation search engine for queries pp1290 - 1292
Robert W. Shafer, Duane R. Jung
& Bradley J. Betts
doi:10.1038/81407
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(92K)
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On the market p1293
doi:10.1038/81412
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(136K)
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