1
Malaria Program, Naval Medical Research Center,
Silver Spring MD 20910-7500
2
Department of Molecular Microbiology and Immunology,
School of Hygiene and Public Health, Johns Hopkins University,
Baltimore MD 21205-2179 hoffmans@nmrc.navy.mil
Developing a modern vaccine that is able to duplicate the protective
immunity observered after immunization with irradiated P. falciparum
(Pf) sporozoites requires identification of antigenic Pf proteins. The identification
of Pf Liver Stage Antigen-3 and its ability to protect chimpanzees against
sporozoite challenge suggests we are headed in the right direction (pages 1258−1263).
