Division of Pediatric Hematology-Oncology Children's
Hospital and Dana Farber Cancer Institute Harvard Medical School Howard Hughes
Medical Institute Boston, MA 02115
orkin@rascal.med.harvard.edu
The extraordinary plasticity of tissue stem cells, such as the ability
of blood stem cells to differentiate into liver, would intrigue even the ancient
alchemists. Recent discoveries also force us to rethink cell lineage relationships
and expand the potential for cell-based therapies (pages
1229−1234).
