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| Editorial |  Top |
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Untangling huntingtin's mysteries p1063
doi:10.1038/80344
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(62K)
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| Letters to Editor | Top |
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LMP2 expression and proteasome activity in NOD mice p1064
Benedikt M. Kessler, Ana-Maria Lennon-Duménil, Mari L. Shinohara, Myra A. Lipes
& Hidde L. Ploegh
doi:10.1038/80346
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(112K)
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LMP2 expression and proteasome activity in NOD mice pp1064 - 1065
Herbert A. Runnels, Wendy A. Watkins
& John J. Monaco
doi:10.1038/80349
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Reply to 'LMP2 expression and proteasome activity in NOD mice' pp1065 - 1066
Takuma Hayashi, Shohta Kodama
& Denise L. Faustman
doi:10.1038/80353
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(175K)
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| News | Top |
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Results make a monkey of OPV−AIDS theory p1067
Karen Birmingham
doi:10.1038/80356
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(123K)
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Europe asks UK to reject cloning approval ... p1068
David Dickson
doi:10.1038/80361
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(58K)
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... while US scientists push for derivation p1068
Kristine Novak
doi:10.1038/80363
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(58K)
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Pope influences biomedical scientists p1069
Martina Ballmaier
doi:10.1038/80365
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(116K)
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Pediatric study of medicines becomes mandatory p1069
Laura Bonetta
doi:10.1038/80367
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(116K)
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Research legacy of suicide surgeon p1070
Xavier Bosch
doi:10.1038/80370
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(115K)
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Oxford scientists defect to Imperial p1070
Karen Birmingham
doi:10.1038/80373
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(115K)
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Bioinformaticians develop new data mining tools p1071
Eric Niiler
doi:10.1038/80375
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(188K)
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Can Italy catch up in genomics research? p1071
Martina Ballmaier
doi:10.1038/80378
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(188K)
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NIH 'glues' cell biologists together p1072
Alan Dove
doi:10.1038/80380
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(57K)
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Teaching hospitals to share tissue with industry p1072
Tinker Ready
doi:10.1038/80382
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(57K)
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| Commentaries | Top |
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The ubiquitin system pp1073 - 1081
Avram Hershko, Aaron Ciechanover
& Alexander Varshavsky
doi:10.1038/80384
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(297K)
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Hepatitis C Virus and eliminating post-transfusion hepatitis pp1082 - 1086
Harvey J. Alter
& Michael Houghton
doi:10.1038/80394
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(326K)
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From cell physiology to cell physiology pp1087 - 1088
Sydney Brenner
doi:10.1038/80400
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(162K)
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| Book Reviews | Top |
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The Door in the Dream: Conversations With Eminent Women in Science pp1089 - 1090
Reviewed by: Mary-Claire King
doi:10.1038/80403
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(149K)
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Driving Mr. Albert: A trip across America with Einstein's brain p1090
Reviewed by: Steve Horwitz
doi:10.1038/80406
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(97K)
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| News and Views | Top |
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Learning old tricks from new viruses pp1091 - 1092
Karl Münger
doi:10.1038/80409
Abstract | Full text | PDF
(69K)
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Uncoupling diet and diabetes pp1092 - 1093
Leslie P. Kozak
doi:10.1038/80412
Abstract | Full text | PDF
(132K)
See also: Article by Li et al. |
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Containing HIV after infection pp1094 - 1095
Bruce D. Walker
& Eric S. Rosenberg
doi:10.1038/80415
Abstract | Full text | PDF
(215K)
See also: Article by Hel et al. |
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Skin stem cells − a hairy issue. pp1095 - 1097
Colin Jahoda
& Amanda Reynolds
doi:10.1038/80418
Abstract | Full text | PDF
(330K)
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Breaking up receptor alliances: the parting of CD3 and CD4 pp1097 - 1098
Abraham Kupfer
doi:10.1038/80421
Abstract | Full text | PDF
(162K)
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Specific immunotherapy: One size does not fit all pp1098 - 1100
Claude P. Genain
& Scott S. Zamvil
doi:10.1038/80424
Abstract | Full text | PDF
(551K)
See also: Article by Bielekova et al. | Article by Kappos et al. |
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Protecting the female germ line from cancer therapy pp1100 - 1101
Robert F. Casper
& Andrea Jurisicova
doi:10.1038/80427
Abstract | Full text | PDF
(72K)
See also: Article by Morita et al. |
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VEGF gene therapy: stimulating angiogenesis or angioma-genesis? pp1102 - 1103
Peter Carmeliet
doi:10.1038/80430
Abstract | Full text | PDF
(164K)
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'Orphans' meet cholesterol pp1104 - 1105
Alan R. Tall, Phillipe Costet
& Yi Luo
doi:10.1038/80433
Abstract | Full text | PDF
(308K)
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A super way to kill cancer cells? pp1105 - 1106
Barry Halliwell
doi:10.1038/80436
Abstract | Full text | PDF
(85K)
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Research News p1107
Kristine Novak
doi:10.1038/80439
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(111K)
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| Articles | Top |
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Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase
gene or by sphingosine -1-phosphate therapy pp1109 - 1114
Yutaka Morita, Gloria I. Perez, Francois Paris, Silvia R. Miranda, Desiree Ehleiter, Adrianna Haimovitz-Friedman, Zvi Fuks, Zhihua Xie, John C. Reed, Edward H. Schuchman, Richard N. Kolesnick
& Jonathan L. Tilly
doi:10.1038/80442
Abstract | Full text | PDF
(358K)
See also: News and Views by Casper & Jurisicova |
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Skeletal muscle respiratory uncoupling prevents diet-induced obesity
and insulin resistance in mice pp1115 - 1120
Bing Li, Lorraine A. Nolte, Jeong-Sun Ju, Dong Ho Han, Trey Coleman, John O. Holloszy
& Clay F. Semenkovich
doi:10.1038/80450
Abstract | Full text | PDF
(191K)
See also: News and Views by Kozak |
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The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets
the retinoblastoma−E2F pathway and with the oncogene Hras transforms
primary rat cells pp1121 - 1127
Stoyan A. Radkov, Paul Kellam
& Chris Boshoff
doi:10.1038/80459
Abstract | Full text | PDF
(530K)
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Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015) pp1128 - 1133
Stefan J. Ries, Christian H. Brandts, Alicia S. Chung, Carola H. Biederer, Byron C. Hann, Ettie M. Lipner, Frank McCormick
& W. Michael Korn
doi:10.1038/80466
Abstract | Full text | PDF
(255K)
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An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy pp1134 - 1139
Carla Heise, Terry Hermiston, Leisa Johnson, Gabriel Brooks, Adam Sampson-Johannes, Angelica Williams, Lyndah Hawkins
& David Kirn
doi:10.1038/80474
Abstract | Full text | PDF
(187K)
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Viremia control following antiretroviral treatment and therapeutic immunization
during primary SIV251 infection of macaques pp1140 - 1146
Zdenek Hel, David Venzon, Monita Poudyal, Wen-Po Tsai, Laura Giuliani, Ruth Woodward, Claire Chougnet, Gene Shearer, John D. Altman, David Watkins, Norbert Bischofberger, Alashle Abimiku, Phillip Markham, James Tartaglia
& Genoveffa Franchini
doi:10.1038/80481
Abstract | Full text | PDF
(214K)
See also: News and Views by Walker & Rosenberg |
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Secretory leukocyte protease inhibitor mediates non-redundant functions
necessary for normal wound healing pp1147 - 1153
Gillian S. Ashcroft, Kejian Lei, Wenwen Jin, Glenn Longenecker, Ashok B. Kulkarni, Teresa Greenwell-Wild, Hollie Hale-Donze, George McGrady, Xiao-Yu Song
& Sharon M. Wahl
doi:10.1038/80489
Abstract | Full text | PDF
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Dendritic cells genetically modified to express CD40 ligand and pulsed
with antigen can initiate antigen-specific humoral immunity independent of
CD4+ T cells pp1154 - 1159
Toshiaki Kikuchi, Stefan Worgall, Ravi Singh, Malcolm A.S. Moore
& Ronald G Crystal
doi:10.1038/80498
Abstract | Full text | PDF
(221K)
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Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine
pp1160 - 1166
Yu-quan Wei, Qing-ru Wang, Xia Zhao, Li Yang, Ling Tian, You Lu, Bin Kang, Chong-jiu Lu, Mei-juan Huang, Yan-yan Lou, Fei Xiao, Qiu-ming He, Jing-mei Shu, Xing-jiang Xie, Yun-qiu Mao, Shong Lei, Feng Luo, Li-qun Zhou, Chong-en Liu, Hao Zhou, Yu Jiang, Feng Peng, Liang-ping Yuan, Qiu Li, Yang Wu
& Ji-yan Liu
doi:10.1038/80506
Abstract | Full text | PDF
(250K)
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Encephalitogenic potential of the myelin basic protein peptide (amino
acids 83−99) in multiple sclerosis: Results of a phase II clinical trial
with an altered peptide ligand pp1167 - 1175
Bibiana Bielekova, Bonnie Goodwin, Nancy Richert, Irene Cortese, Takayuki Kondo, Ghazaleh Afshar, Bruno Gran, Joan Eaton, Jack Antel, Joseph A. Frank, Henry F. McFarland
& Roland Martin
doi:10.1038/80516
Abstract | Full text | PDF
(353K)
See also: News and Views by Genain & Zamvil | Article by Kappos et al. |
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Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response
in multiple sclerosis after administration of an altered peptide ligand in
a placebo-controlled, randomized phase II trial pp1176 - 1182
Ludwig Kappos, Giancarlo Comi, Hillel Panitch, Joel Oger, Jack Antel, Paul Conlon, Lawrence Steinman, Giancarlo Comi, Ludwig Kappos, Joel Oger, Hillel Panitch, Alexander Rae-Grant, John Castaldo, Nancy Eckert, Joseph B. Guarnaccia, Pamela Mills, Gary Johnson, Peter A. Calabresi, Carlo Pozzilli, Stefano Bastianello, Elisabetta Giugni, Tatiana Witjas, Patrick Cozzone, Jean Pelletier, Dieter Pöhlau, Horst Przuntek, Volker Hoffmann, Christopher Bever Jr, Eleanor Katz, Michel Clanet, Isabelle Berry, David Brassat, Irene Brunet, Gilles Edan, Pierre Duquette, Ernst-Wilhelm Radue, Dagmar Schött, Carmen Lienert, Alice Taksaoui, M. Rodegher, M. Filippi, Alan Evans, Pierre Bourgouin, Alex Zijdenbos, Shawki Salem, Nicholas Ling, David Alleva, Eric Johnson, Amitabh Gaur, Paul Crowe
& Xin-Jun Liu
doi:10.1038/80525
Abstract | Full text | PDF
(128K)
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Systemic sclerosis immunoglobulin G autoantibodies bind the human cytomegalovirus late protein UL94 and induce apoptosis in human endothelial cells pp1183 - 1186
Claudio Lunardi, Caterina Bason, Riccardo Navone, Enrico Millo, Gianluca Damonte, Roberto Corrocher
& Antonio Puccetti
doi:10.1038/80533
Abstract | Full text | PDF
(209K)
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| New Technology | Top |
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Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice pp1187 - 1190
Dexiang Chen, Ryan L. Endres, Cherie A. Erickson, Kathleen F. Weis, Martha W. McGregor, Yoshihiro Kawaoka
& Lendon G. Payne
doi:10.1038/80538
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(165K)
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On the market pp1190 - 1191
doi:10.1038/80544
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(263K)
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