Protecting the female germ line from cancer therapy
Robert F. Casper
& Andrea Jurisicova
Division of Reproductive Sciences, Department of Obstetrics
and Gynecology Samuel Lunenfeld Research Institute and The University of Toronto
, Toronto, Ontario, Canada.
r.casper@utoronto.ca
A naturally occurring metabolite of ceramide, sphingosine-1-phosphate,
reportedly protects mouse oocytes from chemotherapy and radiation-induced
apoptosis. What is the potential for using ceramide analogs to prevent human
infertility? (pages 1109−1114)
