Pennington Biomedical Research Center,
Baton Rouge, Lousiana 70808, USA
KozakLP@mhs.pbrc.edu
Expression of the uncoupling protein Ucp in skeletal muscle prevents
diet-induced obesity and insulin resistance. Similar effects are seen in response
to increased physical exercise, indicating that pharmacological strategies
designed to manipulate energy expenditure can be used to treat obesity and
diabetes. (pages 1115−1120)