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Germ cell transplantation—a fertile field

Abstract

Spermatogonial cell transplantation from a mouse with a defective soma to a mouse with a compromised germ line re-establishes spermatogenesis. The ability of both of these cell types to resume normal function has implications for fertility treatment (29–34).

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Figure 1: A single Sertoli cell and its associated germ cells, based on those seen within a cross-section through the seminiferous epithelium in the mouse.

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Cooke, H., Saunders, P. Germ cell transplantation—a fertile field. Nat Med 6, 16–17 (2000). https://doi.org/10.1038/71469

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