Nature Medicine
6, 23 - 25 (2000)
doi:10.1038/71487
Sex and the genetic diversity of HIV-1Stuart C. Ray1
& Thomas C. Quinn1, 21
Division of Infectious Diseases, Department of Medicine,
Johns Hopkins University School of Medicine, Baltimore, Maryland 21205. tquinn@jhmi.edu
2
National Institute of Allergy and Infectious Diseases,
National Institutes of Health, Bethesda, Maryland 20892 USA
The genetic variability of HIV-1 is an important aspect of its pathogenesis,
even though studies in men have demonstrated that the viral population is
usually homogeneous during the first months of infection. Now, a large study
comparing men and women shows that even before an antibody response is detectable,
the viral population differs between the sexes (71−75).
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