University of Washington School of Medicine, Fred Hutchinson
Cancer Research Center, 1100 Fairview Ave. North, D2-100, P.O.
Box 19024, Seattle, Washington 98109-1024, USA. pmartin@fhcrc.org
During hematopoietic stem cell transplantation, donor cell subsets mediate
the delicate balance between graft rejection and the development of graft-versus-host
disease. Is it possible to manipulate donor cell populations to facilitate
engraftment of highly enriched hematopoietic stem cells in allogeneic recipients?