Division of Molecular Genetics and Centre of Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
tberns@nki.nl
Despite the numerous oncogene signaling pathways that have been deciphered, no one is really sure whether drugs designed to target them will cause tumor regression in vivo. Several recently developed animal models of tumor induction provide insight into the prospects for oncogene-specific therapeutics.
