Abstract
Evidence for a final common pathway for disorders of the myocardium (pages 246 and 320–330).
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Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure
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References
Georgakopoulous, D. et al. The pathogenesis of familial hypertrophic cardiomyopathy: Early and evolving effects of an α-cardiac myosin heavy chain missense mutation. Nature Med. 5, 327– 330 (1999).
Lim, H.W. & Molkentin, J.D. Calcineurin and human heart failure. Nature Med. 5, 246– 247 (1999).
Badorff, C. et al. Enteroviral protease 2A cleaves dystrophin: Evidence of cytoskeletal disruption in an acquired cardiomyopathy. Nature Med. 5, 320–326 (1999).
Seidman, C.E. & Seidman, J.G. in Molecular Cardiovascular Medicine (ed. Haber, E.) 193–210 (Scientific American Press, New York, 1995).
Watkins, H. et al. Mutations in the genes for cardiac troponin T and α-tropomyosin in hypertrophic cardiomyopathy. N. Engl. J. Med. 332 , 1058–1064 (1995).
Molkentin, J.D. et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93, 215– 228 (1998).
Sussman, M.A. et al. Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science 281,1690–1693 (1998).
Towbin, J.A. The role of cytoskeletal proteins in cardiomyopathies. Curr. Opin. Cell. Biol. 10, 131–139 (1998).
Towbin, J.A. et al. X-linked dilated cardiomyopathy. Molecular genetic evidence of linkage to the Duchenne muscular dystrophy locus. Circulation 87, 1854–1865 ( 1993).
Olson, J.M., Michels, V.V., Thibodeau, S.N., Tai, Y.S. & Keating, M.T. Actin mutations in dilated cardiomyopathy, an inheritable form of heart failure. Science 280, 750–752 (1998).
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Towbin, J., Bowles, K. & Bowles, N. Etiologies of cardiomyopathy and heart failure. Nat Med 5, 266–267 (1999). https://doi.org/10.1038/6474
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DOI: https://doi.org/10.1038/6474
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