Nature Medicine
5, 1348 - 1349 (1999)
doi:10.1038/70909
Aspirin for cancerSteven J. Shiff1
& Basil Rigas1, 2, 31
The Rockefeller University 1230 York
Avenue New York, New York 10021,
USA 2
The American Health Foundation, 1 Dana
Road Valhalla, New York 10595,
USA
3
New York Medical College, 1 Dana Road
Valhalla, New York 10595,
USA
shiffs@rockvak.rockefeller.edu
Cyclooxygenase inhibitors are well known for their anti-inflammatory effects,
but recent data indicate that they are also potent anti-angiogenics. The mechanisms
by which nonsteroidal anti-inflammatory drugs affect cyclooxygenase enzymes,
peptic ulcers, angiogenesis and cancer are complex, but are worth sorting
out (pages 1418−1423).
|
