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| Editorial |  Top |
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South Africa: Setting the wrong example p1
doi:10.1038/4666
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(37K)
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| Letters to Editor | Top |
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HSC clinical trials controversy continues p2
Manuel Buchwald
& Hugh O'Brodovich
doi:10.1038/4667
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(33K)
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DNAVEC gene therapy on course p2
Mamoru Hasegawa
doi:10.1038/4668
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(41K)
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HSC clinical trials controversy continues p3
Nancy Olivieri
doi:10.1038/4819
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(33K)
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| News | Top |
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IAVI advances AIDS vaccine research... p5
Alan Dove
doi:10.1038/4669
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(54K)
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...big steps for a young group p5
Alan Dove
doi:10.1038/4818
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(54K)
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Scientists appeal to revoke funding ban on embryo research p6
Marlene Cimons
& Karen Birmingham
doi:10.1038/4673
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(53K)
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AMDeC announces New York Cancer Project p6
Karen Birmingham
doi:10.1038/4675
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(53K)
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Controversial HSC clinical trials report made public p7
Karen Birmingham
doi:10.1038/4676
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(70K)
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Japan celebrates ten years of the HFSP pp7 - 8
Richard Nathan
doi:10.1038/4677
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(200K)
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US public may gain access to research data p8
Alan Dove
doi:10.1038/4680
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(157K)
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Australian research grant awards remain static p9
Rada Rouse
doi:10.1038/4681
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(46K)
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Researchers benefit at BMS award night p9
Karen Birmingham
doi:10.1038/4682
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(46K)
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Cancer centers set sights on tobacco settlement p10
Alicia Ault
doi:10.1038/4685
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(46K)
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Wellcome survey reveals public mistrust of scientists p10
David Dickson
doi:10.1038/4686
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(46K)
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| Commentary | Top |
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Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog pp11 - 12
Ian Tomlinson
& Walter Bodmer
doi:10.1038/4687
Abstract | Full text | PDF
(40K)
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| Book Reviews | Top |
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Of Flies, Mice and Men p13
Reviewed by: Beatrice Renault
doi:10.1038/4670
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(44K)
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The Baltimore Case pp13 - 14
Reviewed by: Fintan R. Steele
doi:10.1038/4689
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(60K)
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| News and Views | Top |
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Tobacco—the growing epidemic pp15 - 17
Richard Peto, Zheng−Ming Chen
& Jillian Boreham
doi:10.1038/4691
Abstract | Full text | PDF
(144K)
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Substitutes for success pp17 - 18
Morris A. Blajchman
doi:10.1038/4694
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(43K)
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Is autoimmunity coming to a Fas(t) end? pp19 - 20
Thomas Brunner
& Christoph Mueller
doi:10.1038/4695
Abstract | Full text | PDF
(137K)
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Cytotoxic T cells: Double-barreled shot guns p20
Thomas Brunner
& Christoph Mueller
doi:10.1038/4697
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(35K)
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AAVant-garde gene therapy pp21 - 22
R. Michael Linden
& Savio L.C. Woo
doi:10.1038/4698
Abstract | Full text | PDF
(70K)
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Bridge over troubled waters pp22 - 23
Hannu Sariola
& Lennart Philipson
doi:10.1038/4700
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(66K)
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Of methods and mapping pp24 - 25
Terence H. Rabbitts
doi:10.1038/4702
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(64K)
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Fatal attraction: When chaperone turns harlot pp25 - 26
Roy Quinlan
& Paul van den IJssel
doi:10.1038/4704
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(53K)
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Unraveling the strands of HIV's web pp27 - 28
Giuseppe Pantaleo
doi:10.1038/4706
Abstract | Full text | PDF
(65K)
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Autoimmune T cells—not always the bad guys p28
Kristine Novak
doi:10.1038/4708
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(42K)
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| Articles | Top |
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Killing HIV-infected cells by transduction with an HIV protease-activated
caspase-3 protein pp29 - 33
Adita M. Vocero-Akbani, Nancy Vander Heyden, Natalie A. Lissy, Lee Ratner
& Steven F. Dowdy
doi:10.1038/4710
Abstract | Full text | PDF
(316K)
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In vivo migration and function of transferred HIV-1-specific cytotoxic
T cells pp34 - 41
Scott J. Brodie, Deborah A. Lewinsohn, Bruce K. Patterson, Daniel Jiyamapa, John Krieger, Lawrence Corey, Philip D. Greenberg
& Stanley R. Riddell
doi:10.1038/4716
Abstract | Full text | PDF
(356K)
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Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits
T cell-mediated autoimmune diseases pp42 - 48
Tong Zhou, Ling Song, Pingar Yang, Zheng Wang, Di Lui
& Richard S. Jope
doi:10.1038/4723
Abstract | Full text | PDF
(204K)
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Autoimmune T cells protect neurons from secondary degeneration after
central nervous system axotomy pp49 - 55
Gila Moalem, Raya Leibowitz−Amit, Eti Yoles, Felix Mor, Irun R. Cohen
& Michal Schwartz
doi:10.1038/4734
Abstract | Full text | PDF
(324K)
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Long-term correction of canine hemophilia B by gene transfer of blood
coagulation factor IX mediated by adeno-associated viral vector pp56 - 63
Roland W. Herzog, Edmund Y. Yang, Linda B. Couto, J. Nathan Hagstrom, Dan Elwell, Paul A. Fields, Melissa Burton, Dwight A. Bellinger, Marjorie S. Read, Kenneth M. Brinkhous, Gregory M. Podsakoff, Timothy C. Nichols, Gary J. Kurtzman
& Katherine A. High
doi:10.1038/4743
Abstract | Full text | PDF
(204K)
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Correction of hemophilia B in canine and murine models using recombinant
adeno-associated viral vectors pp64 - 70
Richard O. Snyder, Carol Miao, Leonard Meuse, Julie Tubb, Brian A. Donahue, Hui-Feng Lin, Darrel W. Stafford, Salil Patel, Arthur R. Thompson, Timothy Nichols, Marjorie S. Read, Dwight A. Bellinger, Kenneth M. Brinkhous
& Mark A. Kay
doi:10.1038/4751
Abstract | Full text | PDF
(384K)
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Human fibroblast growth factor receptor 1 is a co-receptor for infection
by adeno-associated virus 2 pp71 - 77
Keyun Qing, Cathryn Mah, Jonathan Hansen, Shangzhen Zhou, Varavani Dwarki
& Arun Srivastava
doi:10.1038/4758
Abstract | Full text | PDF
(227K)
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 V 5 integrin: a co-receptor for adeno-associated virus type
2 infection pp78 - 82
Candace Summerford, Jeffrey S. Bartlett
& Richard Jude Samulski
doi:10.1038/4768
Abstract | Full text | PDF
(107K)
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Directly measured kinetics of circulating T lymphocytes in normal and
HIV-1-infected humans pp83 - 89
M. Hellerstein, M.B. Hanley, D. Cesar, S. Siler, C. Papageorgopoulos, E. Wieder, D. Schmidt, R. Hoh, R. Neese, D. Macallan, S. Deeks
& J.M. McCune
doi:10.1038/4772
Abstract | Full text | PDF
(117K)
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Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells pp90 - 96
G. Bossi
& G.M. Griffiths
doi:10.1038/4779
Abstract | Full text | PDF
(645K)
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Caspase inhibition reduces apoptosis and increases survival of nigral
transplants pp97 - 100
Gabriele S. Schierle, Oskar Hansson, Marcel Leist, Pierluigi Nicotera, Håkan Widner
& Patrik Brundin
doi:10.1038/4785
Abstract | Full text | PDF
(139K)
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Increased vulnerability of hippocampal neurons to excitotoxic necrosis
in presenilin-1 mutant knock-in mice pp101 - 106
Qing Guo, Weiming Fu, Bryce L. Sopher, Miles W. Miller, Carol B. Ware, George M. Martin
& Mark P. Mattson
doi:10.1038/4789
Abstract | Full text | PDF
(212K)
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Fibrinogen-coated albumin microcapsules reduce bleeding in severely thrombocytopenic
rabbits pp107 - 111
Marcel Levi, Philip W. Friederich, Sarah Middleton, Philip G. de Groot, Ya Ping Wu, Roy Harris, Bart J. Biemond, Harry F.G. Heijnen, Jack Levin
& Jan Wouter ten Cate
doi:10.1038/4795
Abstract | Full text | PDF
(129K)
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Accelerated transport and maturation of lysosomal −galactosidase
A in Fabry lymphoblasts by an enzyme inhibitor pp112 - 115
Jian-Qiang Fan, Satoshi Ishii, Naoki Asano
& Yoshiyuki Suzuki
doi:10.1038/4801
Abstract | Full text | PDF
(105K)
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| New Technology | Top |
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Gene expression profiles of laser-captured adjacent neuronal subtypes
pp117 - 122
Lin Luo, Ranelle C. Salunga, Hongqing Guo, Anton Bittner, K.C. Joy, Jose E. Galindo, Huinian Xiao, Kathryn E. Rogers, Jackson S. Wan, Michael R. Jackson
& Mark G. Erlander
doi:10.1038/4806
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(964K)
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On the market pp122 - 123
doi:10.1038/4813
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(120K)
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