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Nature Medicine  4, 894 - 895 (1998)
doi:10.1038/nm0898-894

Planting new targets for antiparasitic drugs

Robert G. Ridley1

1Pharma Research, Preclinical Infectious Diseases, F. Hoffmann-La Roche, CH-4070 Basel, Switzerland, e-mail: robert_g.ridley@roche.com

An organelle in apicomplexan parasites including those causing malaria and toxoplasmosis may be the site of a plant biosynthetic pathway that could provide new targets for drug discovery and development.

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  10. Donald, R.G.K. & Roos, D.S. Gene knock-outs and allelic replacements in Toxoplasma gondii: HXGPRT as a selectable marker for 'hit and run' mutagenesis. Mol. Biochem. Parasitol. 91, 295−305 (1998). | Article | PubMed  | ISI | ChemPort |
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ISSN: 1078-8956
EISSN: 1546-170X
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