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Commentary
Nature Medicine  4, 882 - 885 (1998)
doi:10.1038/nm0898-882

Self-organization, complexity and chaos: The new biology for medicine

Donald S. Coffey

The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, Maryland 21287, USA

The self-organization of cells into complex interacting systems can be described using a branch of mathematics called nonlinear dynamics, which includes the study of chaos. Here, Donald Coffey explains how analysis of complex biological systems using nonlinear dynamics sheds light on the events leading to disorders as varied as epilepsy, heart disease and cancer

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