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Although the most severe Herpes Simplex Virus-related symptoms seem to occur in patients with impaired cell-mediated immunity, until recently it appeared that patients who seemed to better control the infection showed little by way of anti-HSV cytotoxic T lymphocyte responses. Lawrence Corey and colleagues explain.
The widely used inhalational general anesthetic nitrous oxide inhibits the NMDA class of glutamate-activated receptor channels at clinically relevant concentrations (pages 460–463).
Two different forms of Ebola glycoprotein mediate viral entry into endotheiial cells and block activation of neutrophils resulting in hemorrhage and an impaired immune response.
Humans exposed to simian retroviruses can occasionally become infected, but the real concern is whether human to human spread will occur, as in AIDS (pages 403–407).
