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Nature Medicine  4, 153 - 155 (1998)
doi:10.1038/nm0298-153

BMT beats autoimmune disease

Robert Krance & Malcolm Brenner

Texas Children's Cancer Center, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas 77030, USA. email: rakrance@msmail.his.tch.tmc.edu

Early clinical trial results show that bone marrow stem cell transplantation for patients with severe autoimmune disease is safe and effective.

REFERENCES
  1. Burt, R.K., Burns, W. & Hess, A. Bone marrow transplantation for multiple sclerosis. Bone Marrow Transplant. 16, 1−6 (1995). | PubMed  | ISI | ChemPort |
  2. Shizuru, J.A., Jerabek, L., Edwards, C.T. & Weissman, I.L. Transplantation of purified hematopoietic stem cells: requirements for overcoming the barriers of allogeneic engraftment. Biology of Blood and Marrow Transplantation 2, 3−14 (1996). | PubMed  | ChemPort |
  3. Ishida, T. et al. Requirement of donor-derived stromal cells in the bone marrow for successful allogeneic bone marrow transplantation. J. Immunol. 152, 3119−3127 (1994). | PubMed  | ISI | ChemPort |
  4. Knaan-Shanzer, S., Houben, P., Kinel-Bohre, E.P. & van Bekkum, D.W. Remission induction of adjuvant arthritis in rats by total body irradiation and autologous bone marrow transplantation. Bone Marrow Transplant. 8, 333−338 (1991). | PubMed  | ChemPort |
  5. Tyndall, A. & Gratwohl, A. Blood and marrow stem cell transplants in autoimmune disease: a consensus report written on behalf of the European league against rheumatism (eular) and the European group for blood and marrow transplantation (ebmt). Bone Marrow Transplant. 19, 643−645 (1997). | Article | PubMed  | ChemPort |
  6. Euler, H.H. et al. Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation. Blood 88, 3621−3625 (1997). | ISI |
  7. Passweg, J.R. et al. Autologous stem cell transplantation for autoimmune disease. A preliminary report. Blood 90, 233a (1997).
  8. Fassas, A. et al. Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: first results of a pilot study. Bone Marrow Transplant. 20, 631−638 (1997). | Article | PubMed  | ChemPort |
  9. Burt, R.K. et al. T-cell depleted autologous hematopoietic stem cell transplantation for multiple sclerosis: report of the first three patients. Blood 90, 383a (1997).
  10. Burt, R.K., Traynor, A. & Ramsey-Goldman, R. Hematopoietic stem-cell transplantation for systemic lupus erythematosus. New England J. Med. 337, 1777−1778 (1997). | Article | ISI | ChemPort |
  11. Tyndall, A. et al. Treatment of systemic sclerosis with autologous haemopoietic stem cell transplantation. Lancet 349, 254 (1997). | PubMed  | ISI | ChemPort |
  12. Joske, D.J., Ma, D.T., Langlands, D.R. & Owen, E.T. Autologous bone-marrow transplantation for rheumatoid arthritis. Lancet 350, 337−338 (1997). | PubMed  | ISI | ChemPort |
  13. Marmont, A.M., van Lint, M.T., Gualandi, F. & Bacigalupo, A. Autologous marrow stem cell transplantation for severe systemic lupus erythematosus of long duration. Lupus 6, 545−548 (1997). | PubMed  | ISI | ChemPort |
  14. Rooney, C. et al. Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation. Lancet 345, 9−13 (1995). | Article | PubMed  | ISI | ChemPort |
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ISSN: 1078-8956
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