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News and Views
Nature Medicine  4, 1362 - 1364 (1998)
doi:10.1038/3945

SOD1 aggregates in ALS: Cause, correlate or consequence?

Robert H. Brown Jr.

Day Neuromuscular Research Laboratory Massachusetts General Hospital Charlestown, Massachusetts 02129, USA brown @ helix.mgh.harvard.edu

Increased expression of wild-type SOD1 in mice with ALS does not slow disease progression or diminish the pathological changes in motor neurons.

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