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Nature Medicine  4, 1124 - 1125 (1998)
doi:10.1038/2619

Lowered leptin slims immune response

Jeffrey S. Flier

Department of Medicine, Division of Endocrinology, Beth Israel Deaconess Medical Center Boston, Massachusetts 02215 USA jflier@bidmc.harvard.edu

The decrease in leptin induced by starvation causes immune suppression, further demonstrating that falling and rising leptin levels have major, and quite distinct, physiologic consequences.

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