Nature Medicine
3, 954 - 955 (1997)
doi:10.1038/nm0997-954
Caspases: A treatment target for neurodegenerative disease?David M. Holtzman1, 2
& Mohanish Deshmukh2
1Department of Neurology, Washington University School of Medicine St. Louis, Missouri 63110, USA
2Department of Molecular Biology & Pharmacology, Washington University School of Medicine St. Louis, Missouri 63110, USA Treating neurodegenerative disease with drugs that inhibit the activity of caspases (proteases that regulate apoptosis) is a therapeutic avenue beginning to be explored.
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