Nature Medicine
3, 502 - 504 (1997)
doi:10.1038/nm0597-502
A role for nitric oxide synthase in urinary "urge syndrome"Karl-Erik AnderssonDepartment of Clinical Pharmacology, Lund University Hospital, S-221 85 Lund, Sweden Bladder abnormalities in mice deficient in neuronal nitric oxide synthase may model idiopathic voiding disorders in humans (pages 571−574). REFERENCES
- Jollys, J.V. et al. Does sexual equality extend to urinary symptoms? Neurourol. Urodyn. 12, 391−392 (1993).
- Lepor, H. & Machi, G. Comparison of the AUA symptom index in unselected males and females between 55 and 79 years of age. Urology 42, 36−40 (1993). | Article | PubMed | ISI | ChemPort |
- Abrams, P. New words for old: Urinary tract symptoms for "prostatism". Br. Med. J. 308, 929−930 (1994). | ISI | ChemPort |
- Burnett, A.L. et al. Urinary bladder−urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans. Nature Med. 3, 571−574 (1997). | Article | PubMed | ISI | ChemPort |
- Andersson, K.-E. & Persson, K. Nitric oxide synthase and the lower urinary tract: Possible implications for physiology and pathophysiology. Scand. J. Urol. Nephrol. 29 (Suppl. 175), 43−53 (1995).
- Burnett, A.L. Nitric oxide control of lower genitourinary tract functions: A review. Urology 45, 1071−1083 (1995). | Article | PubMed | ISI | ChemPort |
- Hindmarsh, J.R., Gosling, P.T. & Deane, A.M. Bladder instability: Is the primary defect in the urethra?. Br. J. Urol. 55, 648−651 (1983). | PubMed | ISI | ChemPort |
- McGuire, E.J. Detrusor response to outlet obstruction. World J. Urol. 2, 208−210 (1984). | ISI |
- Persson, K., Igawa, Y., Mattiasson, A. & Andersson, K.-E. Effects of inhibition of the L-arginine/nitric oxide pathway in the rat lower urinary tract in vivo and in vitro. Br. J. Pharmacol. 107, 178−184 (1992). | PubMed | ISI | ChemPort |
- Mevorach, R.A., Bogaert, G.A. & Kogan, B.A. Role of nitric oxide in fetal lower urinary tract function. J. Virol. 152, 510−514 (1994). | ChemPort |
- Bennett, B.C. et al. Neural control of urethral outlet activity in vivo: Role of nitric oxide. J. Urol. 153, 2004−2009 (1995). | Article | PubMed | ISI | ChemPort |
- Sutherland, R.S., Kogan, B.A., Piechota, H.J. & Bredt, D.S. Vesicourethral function in mice with genetic disruption of neuronal nitric oxide synthase. J. Urol. 157, 1109−1116 (1997). | Article | PubMed | ISI | ChemPort |
- Flood, H.D., Fraser, M.O., Yoshiyama, M., Somogyi, G.T. & de Groat, W.C. Nitric oxide (NO) mediated urethral relaxation is present in vivo in the female but not in the male rat. J. Urol. 153, 135A (1995).
- Bedell, M.A., Jenkins, N.A. & Copeland, N.G. Mouse models of human disease. Part I. Techniques and resources for genetic analysis in mice. Genes Devel. 11, 1−10 (1997). | PubMed | ISI | ChemPort |
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