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Nature Medicine  3, 501 - 502 (1997)
doi:10.1038/nm0597-501

DNA vaccination for HIV

Ronald C. Kennedy

Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73109, USA

Studies in chimpanzees provide preliminary evidence that DNA vaccines may protect against experimental infection with HIV-1 (pages 526−532).

REFERENCES
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  2. Cohen, J. Naked DNA points the way to vaccines. Science 259, 1691−1692 (1993). | PubMed  | ChemPort |
  3. McDonnell, W.M. & Askari, F.K. DNA vaccines. N. Engl. J. Med. 334, 42−45 (1996). | Article | PubMed  | ISI | ChemPort |
  4. Baltimore, D. Lessons from people with nonprogressive HIV infection. N. Engl. J. Med. 332, 259−260 (1995). | Article | PubMed  | ISI | ChemPort |
  5. Haynes, B.F., Pantaleo, G. & Fauci, A.S. Toward an understanding of the correlates of protective immunity to HIV infection. Science 271, 324−328 (1996). | PubMed  | ISI | ChemPort |
  6. Cao, Y., Qin, L., Zhang, L., Safrit, J. & Ho, D.D. Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection. N. Engl. J. Med. 332, 201−208 (1995). | Article | PubMed  | ISI | ChemPort |
  7. Rinaldo, C. et al. High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1 infected long-term non-progressors. J. Virol. 69, 5838−5842 (1995). | PubMed  | ISI | ChemPort |
  8. Fouts, T.R. et al. Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex. J. Virol. 71, 2779−2785 (1997). | PubMed  | ISI | ChemPort |
  9. Wang, B. et al. Gene inoculation generates immune responses against human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 90, 4156−4160 (1993). | PubMed  | ChemPort |
  10. Wang, B. et al. Induction of humoral and Cellular immune responses to the human immunodeficiency type 1 virus in nonhuman primates by in vivo DNA inoculation. Virology 211, 102−112 (1995). | Article | PubMed  | ISI | ChemPort |
  11. Lu, S. et al. Simian immunodeficiency virus DNA vaccine trial in macaques. J. Virol. 70, 3978−3991 (1996). | PubMed  | ISI | ChemPort |
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ISSN: 1078-8956
EISSN: 1546-170X
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