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Nature Medicine  3, 493 - 494 (1997)
doi:10.1038/nm0597-493

Estrogen receptor bold beta — Getting in on the action?

Jan-Åke Gustafsson

Departments of Medical Nutrition and Bioscience Novum HS, Karolinska Institutet S-141 86 Huddinge, Sweden

Recent findings in mice hint that ERbeta and not ERalpha may mediate some of the cardiovascular benefits of estrogen (pages 545−548).

REFERENCES
  1. Kuiper, G.G.M.J., Enmark, E., Pelto-Huikko, M., Nilsson, S. & Gustafsson, J-Å. Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. USA 93, 5925−5930 (1996). | Article | PubMed  | ChemPort |
  2. Kuiper, G.G.M.J. et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptor alpha and beta. Endocrinology 138, 863−870 (1997). | Article | PubMed  | ISI | ChemPort |
  3. Byers, M., Kuiper, G.G.J.M., Gustafsson, J-Å & Park-Sarge, O-K. Estrogen receptor-beta mRNA expression in rat ovary: Down regulation by gonadotropins. Mol. Endocrinol. 11, 172−182 (1997). | Article | PubMed  | ISI | ChemPort |
  4. Mosselman, S., Polman, J. & Dijkema, R., ERbeta: Identification and characterization of a novel human estrogen receptor. FEBS Lett. 392, 49−53 (1996) | Article | PubMed  | ISI | ChemPort |
  5. Tremblay, G.B. et al. Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta. Mol. Endocrinol. 11, 353−365 (1997). | Article | PubMed  | ISI | ChemPort |
  6. Shughrue, P.J., Komm, B. & Merchenthaler, I. The distribution of estrogen receptor-beta mRNA in the rat hypothalamus. Steroids 61, 678−681 (1996). | Article | PubMed  | ISI | ChemPort |
  7. Korach, K.S. et al. Estrogen receptor gene disruption: Molecular characterization and experimental and clinical phenotypes. Recent Prog. HOrm. Res. 51, 159−186 (1996). | PubMed  | ISI | ChemPort |
  8. lafrati, M.D. et al. Estrogen inhibits the vascular injury response in estrogen receptor alpha-deficient mice. Nature Med. 3, 545−548 (1997). | Article | PubMed  |
  9. Wilson, J.D., Griffin, J.E. & Russell, D.W. Steroid 5 alpha-reductase 2 deficiency. Endocr. Rev. 14, 577−593 (1993). | Article | PubMed  | ISI | ChemPort |
  10. Kruithof-Dekker, I.G., Tetu, B., Janssen, P.J. & Vander Kwast, T.H. Elevated estrogen receptor expression in human prostatic stromal cells by androgen ablation therapy. J. Urol. 156, 1194−1197 (1996). | Article | PubMed  | ChemPort |
  11. Katzenellenbogen, B.S. et al. Antiestrogens: Mechanisms and actions in target cells. J. Steroid Biochem. Mol. Biol. 53, 387−393 (1995). | Article | PubMed  | ISI | ChemPort |
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ISSN: 1078-8956
EISSN: 1546-170X
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