Human TSE disease — viral or protein only?

1. Caughey, B. & Chesebro, B. Prion protein and the transmissible spongiform encephalopathies. Trends Biol. Sci. 7, 56−62 (1997). | Article | ChemPort |
2. Griffith, J.S. Self-replication and scrapie. Nature 215, 1043−1044 (1967). | PubMed  | ISI | ChemPort |
3. Prusiner, S.B. Novel proteinaceous infectious particles cause scrapie. Science 216, 136−144 (1982). | PubMed  | ISI | ChemPort |
4. Gajdusek, D.C. Transmissible and nontransmissible amyloidoses: Autocatalytic post-translational conversion of host precursor proteins to beta-pleated configurations. J. Neuroimmunol. 20, 95−110 (1988). | Article | PubMed  | ISI | ChemPort |
5. Hsiao, K.K. et al. Spontaneous neurodegeneration in transgenic mice with mutant prion protein. Science 250, 1587−1590 (1990). | PubMed  | ISI | ChemPort |
6. Westaway, D. et al. Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell 76, 117−129 (1994). | Article | PubMed  | ISI | ChemPort |
7. Hsiao, K.K. et al. Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proc. Natl. Acad. Sci. USA 91, 9126−9130 (1994). | PubMed  | ChemPort |
8. Brown, P. et al. Human spongiform encephalopathy: The National Institutes of Health series of 300 cases of experimentally transmitted disease. Ann. Neurol. 35, 513−529 (1994). | PubMed  | ISI | ChemPort |
9. Silvestrini, M.C. et al. Identification of the prion protein allotypes that accumulate in the brain of sporadic and familial Creutzfeldt-jakob disease patients. Nature Med. 3, 521−525 (1997). | Article | PubMed  | ISI | ChemPort |
10. Tagliavini, F. et al. Amyloid fibrils in Gerstmann-Straussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant allele. Cell 79, 695−703 (1994). | PubMed  | ISI | ChemPort |
11. Barbanti, P. et al. Polymorphism at codon 129 or codon 219 of PRNP and clinical heterogeneity in a previously unreported family with Gerstmann-Straussler-Scheinker disease (PrP-P102L mutation). Neurology 47, 734−741 (1996). | PubMed  | ISI | ChemPort |
12. Gabizon, R. et al. Insoluble wild-type and protease-resistant mutant protein in brains of patients with inherited prion disease. Nature Med. 2, 59−64 (1996). | Article | PubMed  | ISI | ChemPort |
13. Kitamoto, T., Yamaguchi, K., Doh-ura, K. & Tateishi, J.A prion protein missense variant is integrated in kuru plaque cores in patients with Gerstmann-Straussler syndrome. Neurology 41, 306−310 (1991). | PubMed  | ISI | ChemPort |
14. Young, N.S., . in Fields Virology. (eds. Fields B.N., Knipe, D.M. & Howley P.M.) 2199−2220 (Lippincott-Raven, Philadelphia, 1996).
15. Goldfarb, L.G. et al. Creutzfeldt-Jacob disease associated with the PRNP codon 200Lys mutation: an analysis of 45 families. Eur. J. Epidemiol. 7, 477−486 (1991). | PubMed  | ISI | ChemPort |
16. Pocchiari, M. et al. A new point mutation of the prion protein gene in Creutzfeldt-jakob disease. Ann. Neural. 34, 802−807 (1993). | ChemPort |

	Top

	Top