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| Editorial | Top |
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The bottom line p365 Barbara J. Culliton doi:10.1038/nm0497-365 PDF
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| Letters to the Editor | Top |
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Less stress more pressure? p366 Robert A. Fishman doi:10.1038/nm0497-366a References | PDF
(132K)
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Less stress more pressure? p366 Hermona Soreq, Daniela Kaufer
& Alon Friedman doi:10.1038/nm0497-366b References | PDF
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To test, or not to test? p366 Tom S. Frank doi:10.1038/nm0497-366c PDF
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HIV-1 antibody debris or virion? pp366 - 367 Paul W.H.I. Parren, Dennis R. Burton
& Quentin J. Sattentau doi:10.1038/nm0497-366d References | PDF
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HIV-1 co-receptors binding pp367 - 368 Shibo Jiang doi:10.1038/nm0497-367 References | PDF
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Transmission of L. infantum by blood donors p368 Joanna Kubar, Jean-François Quaranta, Pierre Marty, Alain Lelièvre, Yves Le Fichoux
& Jean-Pierre Aufeuvre doi:10.1038/nm0497-368 References | PDF
(502K)
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| News | Top |
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Easier access to clinical trials p369 Barbara J. Culliton doi:10.1038/nm0497-369a PDF
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Hughes expands in the Americas pp369 - 370 Barbara J. Culliton doi:10.1038/nm0497-369b PDF
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Reactions to cloning p370 Marlene Cimons doi:10.1038/nm0497-370a PDF
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... and home on the farm pp370 - 371 David Dickson doi:10.1038/nm0497-370b PDF
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Japan considers ethics of genetic screening p371 Richard Nathan doi:10.1038/nm0497-371a PDF
(258K)
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... and Britain considers impact on life insurance p371 David Dickson doi:10.1038/nm0497-371b PDF
(258K)
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NY hospitals win education subsidy p372 Barbara J. Culliton doi:10.1038/nm0497-372a PDF
(366K)
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HIV CCR5 resistance incomplete pp372 - 373 Orla Smith doi:10.1038/nm0497-372b PDF
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Japan forges ahead on artificial organs p373 doi:10.1038/nm0497-373 PDF
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| Commentary | Top |
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Rational design of vaccines pp374 - 376 Rino Rappuoli doi:10.1038/nm0497-374 Abstract + references | PDF
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| News and Views | Top |
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Selectivity of general anesthetics: A new dimension pp377 - 378 Nicholas P. Franks
& William R. Lieb doi:10.1038/nm0497-377 Abstract + references | PDF
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Multidrug resistance a multiplex phenomenon pp378 - 380 Nicola Baldini doi:10.1038/nm0497-378 Abstract + references | PDF
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Gene therapy for motor neuron disease pp380 - 381 Michael Sendtner doi:10.1038/nm0497-380 Abstract + references | PDF
(224K)
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T lymphocytes: Setting the tone of the airways pp382 - 383 Erwin W. Gelfand
& Charles G. Irvin doi:10.1038/nm0497-382 Abstract + references | PDF
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Managed care for viruses pp383 - 384 Ronald G. Crystal doi:10.1038/nm0497-383 Abstract + references | PDF
(252K)
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Fibrillation, chaos and clinical control pp385 - 386 Max J. Lab doi:10.1038/nm0497-385 Abstract + references | PDF
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Thyroiditis and hepatitis: Fas on the road to disease pp387 - 388 Lars E. French
& Jürg Tschopp doi:10.1038/nm0497-387 Abstract + references | PDF
(264K)
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| Review | Top |
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HIV accessory proteins as therapeutic targets pp389 - 394 Roger H. Miller
& Nava Sarver doi:10.1038/nm0497-389 Abstract + references | PDF
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| Articles | Top |
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Identification of compounds with preferential inhibitory activity against low-Nm23-expressing human breast carcinoma and melanoma cell lines pp395 - 401 José M.P. Freije, Julia A. Lawrence, Melinda G. Hollingshead, Abel De La Rosa, Ven Narayanan, Michael Grever, Edward A. Sausville, Kenneth Paull
& Patricia S. Steeg doi:10.1038/nm0497-395 Abstract + references | PDF
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Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice pp402 - 408 Karen A. Klein, Robert E. Reiter, James Redula, Hamid Moradi, Xaio Lin Zhu, Arthur R. Brothman, Dolores J. Lamb, Marco Marcelli, Arie Belldegrun, Owen N. Witte
& Charles L. Sawyers doi:10.1038/nm0497-402 Abstract + references | PDF
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Essential roles of the Fas ligand in the development of hepatitis pp409 - 413 Toru Kondo, Takashi Suda, Hidehiro Fukuyama, Masashi Adachi
& Shigekazu Nagata doi:10.1038/nm0497-409 Abstract + references | PDF
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Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein pp414 - 420 Lyuba Benimetskaya, John D. Loike, Zahangir Khaled, Gila LoiKe, Samuel C. Silverstein, Long Cao, Joseph E.L. Khoury, Tian-Quan CaI
& C.A. Stein doi:10.1038/nm0497-414 Abstract + references | PDF
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Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A pp421 - 428 Joseph P. Steiner, Maureen A. Connolly, Heather L. Valentine, Gregory S. Hamilton, Ted M. Dawson, Lynda Hester
& Solomon H. Snyder doi:10.1038/nm0497-421 Abstract + references | PDF
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Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors pp429 - 436 G. Haase, P. Kennel, B. Pettmann, E. Vigne, S. Akli, F. Revah, H. Schmalbruch
& A. Kahn doi:10.1038/nm0497-429 Abstract + references | PDF
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Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth pp437 - 442 Toshihide Tanaka, Yoshinobu Manome, Patrick Wen, Donald W. Kufe
& Howard A. Fine doi:10.1038/nm0497-437 Abstract + references | PDF
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Critical components of the female reproductive pathway are suppressed by the angiogenesis inhibitor AGM-1470 pp443 - 446 Nancy Klauber, Richard M. Rohan, Evelyn Flynn
& Robert J. D'amato doi:10.1038/nm0497-443 Abstract + references | PDF
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Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression pp447 - 450 Ralf C. Bargou, Karsten Jürchott, Christian Wagener, Stephan Bergmann, Sylvia Metzner, Kurt Bommert, Markus Y. Mapara, Klaus-Jürgen Winzer, Manfred Dietel, Bernd Dörken
& Hans-Dieter Royer doi:10.1038/nm0497-447 Abstract + references | PDF
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Effective tumor vaccines generated by in vitro modification of tumor cells with cytokines and bispecific monoclonal antibodies pp451 - 455 Ya-Jun Guo, Xiao-Yan Che, Feng Shen, Tian-Pei Xie, Jing Ma, Xiao-Ning Wang, Shu-Guang Wu, Donald D. Anthony
& Meng-Chao Wu doi:10.1038/nm0497-451 Abstract + references | PDF
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Elevation of oxygen release by nitroglycerin without an increase in blood flow in the hepatic microcirculation pp456 - 459 Hiroaki Kosaka
& Akitoshi Seiyama doi:10.1038/nm0497-456 Abstract + references | PDF
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T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice pp460 - 462 George T. De Sanctis, Akihiko Itoh, Francis H.Y. Green, Shixin Qin, Toshihisa Kimura, James K. Grobholz, Thomas R. Martin, Takashi Maki
& Jeffrey M. Drazen doi:10.1038/nm0497-460 Abstract + references | PDF
(297K)
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| Book Review | Top |
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The Eleventh Plague: The Politics of Biological and Chemical Warfare p463 doi:10.1038/nm0497-463a PDF
(174K)
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Dying in a Japanese Hospital pp463 - 464 doi:10.1038/nm0497-463b PDF
(439K)
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| New Technology | Top |
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Evaluation of a new rapid bacteriophage-based method for the drug susceptibility testing of Mycobacterium tuberculosis pp465 - 468 Stuart Mark Wilson, Zubaida Al-Suwaidi, Ruth McNerney, John Porter
& Francis Drobniewski doi:10.1038/nm0497-465 References | PDF
(673K)
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On the market pp469 - 471 doi:10.1038/nm0497-469 PDF
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