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Nature Medicine  3, 382 - 383 (1997)
doi:10.1038/nm0497-382

T lymphocytes: Setting the tone of the airways

Erwin W. Gelfand & Charles G. Irvin

Departments of Pediatrics and Medicine National Jewish Medical and Research Center Denver, Colorado 80206, USA

Baseline airway responsiveness is mediated by T cells in mouse models of asthma (pages 460−462).

REFERENCES
  1. DeSanctis, G.T. et al. Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nature Genet. 11, 150−154 (1995). | Article | PubMed  | ISI | ChemPort |
  2. Levitt, R.C., Mitzner, W. & Kleeberger, S.R. A genetic approach to the study of lung physiology: Understanding biological variability in airway responsiveness. Am. J. Physiol. 258, L157−L164 (1990). | PubMed  | ISI | ChemPort |
  3. Renz, H. et al. T Cells expressing specific V elements regulate IgE production and airway responsiveness in vivo. J. Exp. Med. 177, 1175−1180 (1993). | PubMed  | ISI | ChemPort |
  4. Moore, M.W., Cacalano, G. Wood, W.J. & Bailish E. Neutrophilia in mice that lack the murine IL-8 receptor homolog. Science 269, 1590−1591 (1995). | PubMed  |
  5. Hamelmann, E. et al. Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness. Am. J. Resp. Cell. Mol. Biol. (in the press).
  6. Blumenthal, M.N. & Bjorksten, B. eds. Genetics of Allergy and Asthma. (Marcel Dekker, New York, 1997).
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ISSN: 1078-8956
EISSN: 1546-170X
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