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Nature Medicine  3, 146 - 147 (1997)
doi:10.1038/nm0297-146

Preterm birth, cerebral palsy and magnesium

Robert L. Goldenberg & Dwight J. Rouse

University of Alabama at Birmingham 618 South 20th Street, OHB 560 Birmingham, Alabama 35294, USA

Magnesium sulfate administered to pregnant mothers may reduce the risk of cerebral palsy in very preterm infants.

REFERENCES
  1. Andrews, W.W., Coldenberg, R.L. & Hauth, J.C. Preterm labor: Emerging role of genital tract infections. Infect. Agents Dis. 4, 196−211 (1995). | PubMed  | ISI | ChemPort |
  2. Schendel, D.E., Berg, C.J., Yeargin-Allsopp, M., Boyle, C.A. & Decoufle, P. Prenatal magnesium sulfate exposure and the risk for cerebral palsy or mental retardation among very low-birth-weight children aged 3 to 5 years. JAMA 276, 1805−1810 (1996). | Article | PubMed  | ISI | ChemPort |
  3. Saigal, S., Szatmari, P., Rosenbaum, P., Campbell, D. & King, S. Cognitive abilities and school performance of extremely low birth weight children and matched term control children at age 8 years: A regional study. J. Pediatr. 118, 751−760 (1991). | PubMed  | ISI | ChemPort |
  4. McDonald, J.W., Silverstein, F.S. & Johnston, M.V. Magnesium reduces N-methyl-D-aspartate (NMDA)-mediated brain injury in perinatal rats. Neurosci. Lett. 109, 234−238 (1990). | Article | PubMed  | ISI | ChemPort |
  5. Nelson, K.B. & Grether, J.K. Can magnesium sulphate reduce the risk of cerebral palsy in very low birth weight infants? Pediatrics 95, 263−269 (1995). | PubMed  | ISI | ChemPort |
  6. Yoon, B.H. et al. High expression of interleukin-6, interleukin-1, and tumor necrosis factor in periventricular leukomalacia. Am. J. Obstet. Gynecol. SPO Abstr. 174, 319−399 (1996).
  7. Weglicki, W.B., Phillips, T.M., Freedman, A.M., Cassidy, M.M. & Dickens, B.F. Magnesium deficiency elevates circulating levels of inflammatory cytokines and endothelin. Mol. Cell. Biochem. 110, 169−173 (1992). | PubMed  | ISI | ChemPort |
  8. Kass, E.H., Schlievert, P.M., Parsonnet, J. & Mills, J.T. Effect of magnesium on production of toxic-shock-syndrome toxin-1: A collaborative study. J. Infect. Dis. 158, 44−51 (1988). | PubMed  | ISI | ChemPort |
  9. Blair, E., Palmer, L. & Stanely, F. Cerebral palsy in very low birthweight infants, pre-eclampsia and magnesium sulfate. Pediatrics 97, 780−781 (1996). | PubMed  | ISI | ChemPort |
  10. Rouse, D.J., Hauth, J.C., Nelson, K.G. & Goldenberg, R.L. The feasibility of a randomized clinical perinatal trial: Maternal magnesium sulfate for the prevention of cerebral palsy. Am. J. Obstet. Gynecol. 175, 701−705 (1996). | PubMed  | ISI | ChemPort |
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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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