Polyglutamines, nuclear inclusions and neurodegeneration
Astrid Lunkes
& Jean-Louis Mandel
Institut de Genetique etBiologie Moleculaire, Et Cellulaire CNRS/INSERM/Université Louis Pasteur, BP163,67404 Hlkirch Cedex, CU, Strasbourg France
Amyloid-like aggregates of expanded polyglutamines are present in nuclei from affected neurons in Huntington and related neurodegenerative diseases.
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