Two recent studies have shown that alterations in muscle stem cell–niche interactions during aging underlie the functional decline in regenerative potential. The reconstitution of this communication restores stem cell function and enhances skeletal muscle repair.
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Tierney, M., Sacco, A. The role of muscle stem cell–niche interactions during aging. Nat Med 22, 837–838 (2016). https://doi.org/10.1038/nm.4159
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DOI: https://doi.org/10.1038/nm.4159