About the cover

May 2014 Volume 20 No 5

A potential treatment for Huntington's disease involves reducing expression of the mutant gene. In this issue, X William Yang and his colleagues determine to which parts of the mouse brain the treatment should be directed for maximum benefit (p 536). The cover image (courtesy of the authors) demonstrates labeling of the cortex (green) and striatum (purple) and of neurons throughout the brain (red).