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Letters to the Editor
Nature Medicine  2, 610 (1996)
doi:10.1038/nm0696-610a

Reply to "A role for GAPDH in apoptosis and neurodegeneration"

Allen D. Roses, James R. Burke, Jeffery M. Vance & Warren J. Strittmatter

Deane Laboratory, Division of Neurology Duke University Medical Center Durham, North Carolina 27710, USA


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  2. Ishitani, R. et al. Evidence that glyceraldehyde-3-phosphate dehydrogenase is involved in age-induced apoptosis in mature cerebellar neurons in culture. J. Neurochem. 66, 928−935 (1996). | PubMed  | ISI | ChemPort |
  3. Ishitani, R. et al. An antisense oligodeoxynucleotide to glyceraldehyde-3-phosphate dehydrogenase blocks age-induced apoptosis of mature cerebro-cortical neurons in culture. J. Pharmacol. Exp. Ther. (in the press).
  4. Portera-Cailliau, C., Hedreen, J.C., Price, D.L. & Koliatsos, V.E. Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J. Neurosci. 15, 3775−3787 (1995). | PubMed  | ChemPort |
  5. Sunaga, K., Takahashi, H., Chuang, D.-M. & Ishitani, R. Glyceraldehyde-3-phosphate dehydrogenase is over-expressed during apoptotic death of neuronal cultures and is recognized by a monoclonal antibody against amyloid plaques from Alzheimer's brain. Neurosci. Lett. 200, 133−136 (1995). | Article | PubMed  | ISI | ChemPort |
  6. Stott, K., Blackburn, J.M., Butler, P.J.G. & Perutz, M. Incorporation of glutamine repeats makes protein oligomerize: Implications for neurodegenerative diseases. Proc. Natl. Acad. Sci. USA 92, 6509−6513 (1995). | PubMed  | ChemPort |
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ISSN: 1078-8956
EISSN: 1546-170X
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