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Nature Medicine  2, 521 - 522 (1996)
doi:10.1038/nm0596-521

Genetic studies of manic−depressive illness

Kay Redfield Jamison & Melvin G. McInnis

Department of Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-7381, USA

Inconclusive results from linkage studies of bipolar illness mirror the complexity of the disease.

REFERENCES
  1. Poe, E.A. The Fall of the House of Usher and Other Writings (1839; reprint, Penguin Books, London, 1986).
  2. Goodwin, F.K. & Jamison, K.R. Manic-Depressive Illness. (Oxford University Press, New York, 1990).
  3. Regier, D.A. et al. One-month prevalence of mental disorders in the United States: Based on five epidemiological catchment areas. Arch. Gen. Psychiatry 44, 977−986 (1988).
  4. Kessler, R.C. et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the national comorbidity survey. Arch. Gen. Psychiatry 51, 8−19 (1994). | PubMed  | ISI | ChemPort |
  5. Angst, J. The course of major depression, atypical bipolar disorder, and bipolar disorder. in New Results in Depression Research, (eds. Hippius, H., Klerman, G.L. & Matussek, N.) (Springer-Verlag, Berlin, 1986).
  6. Roy-Byrne, P., Post, R.M., Uhde, T.W., Porcu, T. & Davis, D. The longitudinal course of recurrent affective illness: Life chart data from research patients at the NIMH. Ada Psychiatr. Scand. 71 (suppl. 317), 1−34 (1985).
  7. Regier, D.A. et al. Co-morbidity of mental disorders with drug and alcohol abuse: Results from the Epidemiologic Catchment Area (EGA) study. JAMA 264, 2511−2518 (1990). | Article | PubMed  | ISI | ChemPort |
  8. Wyatt, R.L. & Henter, I. An economic evaluation of manic-depressive illness — 1991. Soc. Psychiatry Psychiatr. Epidemiol. 30, 213−219 (1995). | PubMed  | ISI | ChemPort |
  9. Blackwood, D.H.R. et al. A locus for bipolar affective disorder on chromosome 4p. Nature Genet. 12, 427−430 (1996). | Article | PubMed  | ISI | ChemPort |
  10. Ginns, E.I. A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish. Nature Genet. 12, 431−435 (1996). | Article | PubMed  | ISI | ChemPort |
  11. Freimer, N.B. et al. Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22−q23. Nature Genet. 12, 436−441 (1996). | Article | PubMed  | ISI | ChemPort |
  12. Berrettini, W. et al. Chromosome 18 DNA markers and manic-depressive illness: Evidence for a susceptibility gene. Proc. Natl. Acad. Sci. USA 91, 5918−5921 (1994). | PubMed  | ChemPort |
  13. Stine, O.C. et al. Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am. J. Hum. Genet. 57, 1384−1394 (1995). | PubMed  | ISI | ChemPort |
  14. Richards, R.L. Relationships between creativity and psychopathology: An evaluation and interpretation of the evidence. Genet. Psychol. Monogr. 103, 261−324 (1981). | PubMed  | ISI | ChemPort |
  15. Jamison, K.R. Touched With Fire: Manic-Depressive Illness and the Artistic Temperament. (Free Press, New York, 1993).
  16. Baxter, L.R. et al. Cerebral metabolic rates in mood disorders: Studies with positron emission tomography and fluorodeoxyglucose F18. Arch. Gen. Psychiatry 42, 441−447 (1985). | PubMed  | ISI |
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ISSN: 1078-8956
EISSN: 1546-170X
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