Chemokines and HIV−1 second receptors

1. Yoshimura, T.K. & Tanaka, S. Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines. Proc. Natl. Acad. Sci. USA 84, 9233−9237 (1987). | PubMed  | ChemPort |
2. Murphy, P.M. The molecular biology of leukocyte chemoattractant receptors. Annu. Rev. Immunol. 12, 593−633 (1994). | Article | PubMed  | ISI | ChemPort |
3. Nussbaum, O., Broder, C.C. & Berger, E.A. Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating Cell fusion-dependent reporter gene activation. J. Virol. 68, 5411−5422 (1994). | PubMed  | ISI | ChemPort |
4. Litwin, V. et al. Human immunodeficiency virus type 1 membrane fusion mediated by a laboratory-adapted strain and a primary isolate analyzed by resonance energy transfer. J. Virol. 70, 6437−6441 (1996). | PubMed  | ISI | ChemPort |
5. Connor, R.I., Chen, B.K., Choe, S. & Landau, N.R. Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology 206, 936−944 (1995). | Article |
6. Helseth, E. et al. Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants. J. Virol 64, 2416−2420 (1990). | PubMed  | ISI | ChemPort |
7. Sullivan, N., Sun, Y., Li, J., Hofmann, W. & Sodroski, J. Replicate function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates. J. Virol. 69, 4413−4422 (1995). | PubMed  | ISI | ChemPort |
8. Cohen, J. Likely HIV cofactor found. Science 272, 809−810 (1996). | PubMed  | ISI | ChemPort |
9. Walker, C.M., Moody, D.J., Stites, D.P. & Levy, J.A. CD8⁺ lymphocytes can control HIV infection in vitro by suppressing virus replication. Science 234, 1563−1566 (1986). | PubMed  | ISI | ChemPort |
10. Walker, C.M. & Levy, J.A. A diffusable lymphokine produced by CD8⁺ T lymphocytes suppresses HIV replication. Immunology 66, 628−630 (1989). | PubMed  | ISI | ChemPort |
11. Brinchmann, J.E., Gaudernack, G. & Vartdal, F. CD8⁺ cells inhibit HIV replication in naturally infected CD4⁺ cells: Evidence for a soluble inhibitor. J Immunol. 144, 2961−2966 (1990). | PubMed  | ISI | ChemPort |
12. Mackewicz, C.E., Ortega, H.W. & Levy, J.A. CD8 Cell anti-HIV activity correlates with the clinical state of the infected individual. J. Clin. Invest 87, 1462−1466 (1991). | PubMed  | ISI | ChemPort |
13. Gomez, A.M., Smaill, P.M. & Rosenthal, K.L. Inhibition of HIV replication by CD8⁺ T cells correlates with CD4 counts and clinical stage of disease. Clin. Exp. Immunol. 97, 68−75 (1994). | PubMed  | ISI | ChemPort |
14. Cao, Y., Qin, L., Zhang, L., Safrit, J. & Ho, D.D. Virological and immunological characterization of long-term survivors of human immunodeficiency virus type 1 infection. N. Engl. J. Med. 332, 201−208 (1995). | Article | PubMed  | ISI | ChemPort |
15. Powell, D.J. et al. Inhibition of cellular activation of retroviral replication by CD8⁺ T cell derived from non-human primates. Clin. Exp. Immunol. 91, 473−481 (1993). | PubMed  | ISI |
16. Ennen, J. et al. CD8⁺ T lymphocytes of African Green monkeys secrete an immunodeficiency virus-suppressing lymphokine. Proc. Natl. Acad. Sci. USA 91, 7207−7211 (1994). | PubMed  | ChemPort |
17. Castro, B.A., Walker, C.M., Eichberg, J.W. & Levy, J.A. Suppression of human immunodeficiency virus replication by CD8⁺ cells from infected and uninfected chimpanzees. Cell. Immunol. 132, 246−255 (1991). | PubMed  | ISI | ChemPort |
18. Mackewicz, C.E., Ortega, H. & Levy, J.A. Effect of cytokines on HIV replication in CD4⁺ lymphocytes: Lack of identity with the CD8⁺ cell antiviral factor. Cell. Immunol. 153, 329−343 (1994). | Article | PubMed  | ISI | ChemPort |
19. Brinchmann, J.E., Gaudernack, G. & Vartdal, F. In vitro replication of HIV-1 in naturally infected CD4⁺ T cells is inhibited by rIFN alpha2 and by a soluble factor secreted by activated CD8⁺ T cells, but not by rIFN beta, rIFN gamma, or recombinant tumor necrosis factor-alpha. J. Acquir. Immune Defic. Syndr. 4, 480−488 (1991). | PubMed  | ISI | ChemPort |
20. Cocchi, F. et al. Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8⁺ T cells. Science 270, 1811−1815 (1995). | PubMed  | ISI | ChemPort |
21. Moriuchi, H., Moriuchi, M. & Fauci, A.S. CD8⁺ T cell soluble factor (s), but not chemokines RANTES, MIP-1a, and MIP-1b, can suppress HIV-1 replication in the monocyte/macrophage system. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. Abstracts of the 1996 Annual Meeting of the Institute of Human Virology, 9−13 September 1996, Abstr. 18. (1996).
22. Baier, M., Werner, A., Bannert, N., Metzner, K. & Kurth, R. HIV suppression by interleukin-16. Nature 378, 563 (1995). | Article | PubMed  | ISI | ChemPort |
23. Fauci, A.S., Masur, H., Gelmann, E.P., Hahn, B.H. & Lane, H.C. The acquired immunodeficiency syndrome: An update. Ann. Intern. Med. 102, 800−813 (1985). | PubMed  | ISI | ChemPort |
24. Gartner, S. et al. The role of mononuclear phagocytes in HTLV-III/LAV infection. Science 233, 215−219 (1996).
25. Roos, M.T.L. et al. Viral phenotype and immune response in primary human immunodeficiency virus type 1 infection. J. Infect. Dis. 165, 427−432 (1992). | PubMed  | ISI | ChemPort |
26. Schuitemaker, H. et al. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T cell-tropic populations. J. Virol 66, 1354−1360 (1992). | PubMed  | ISI | ChemPort |
27. Conner, R.I. & Ho, D.D. Human immunodeficiency virus type 1 variants with increased replicative capacity develop during the asymptomatic stage before disease progression. J. Virol. 68, 4400−4408 (1994). | PubMed  | ISI | ChemPort |
28. Tersmette, M. et al. Differential syncytium-inducing capacity of human immunodeficiency virus isolates: Frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency virus syndrome (AIDS) and AIDS-related complex. J. Virol 62, 2026−2032 (1988). | PubMed  | ISI | ChemPort |
29. Tersmette, M. et al. Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency virus syndrome: Studies on sequential isolates. J Virol 63, 2118−2125 (1989). | PubMed  | ISI | ChemPort |
30. Tersmette, M. et al. Association between biological properties of human immunodeficiency virus variants and risk for AIDS and AIDS mortality. Lancet 1, 983−985 (1989). | Article | PubMed  | ISI | ChemPort |
31. Dalgleish, A.G. et al The CD4 (T4) antigen is an essential component of the receptor of the AIDS retrovirus. Nature 312, 763−767 (1984). | PubMed  | ISI | ChemPort |
32. Klatzmann, D. et al T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature 312, 20−27 (1984).
33. McDougal, J.S. et al Binding of HTLV-III/LAV to T4⁺ T cells by a complex of the 110K viral protein and the T4 molecule. Science 231, 382−385 (1985). | ISI |
34. Maddon, P.J. et al The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 47, 333−348 (1986). | Article | PubMed  | ISI | ChemPort |
35. Landau, N.R., Warton, M. & Littman, D.R. The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4. Nature 334, 159−162 (1988). | Article | PubMed  | ISI | ChemPort |
36. O'Brien, W.A. etal HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp 120 outside the CD4-binding domain. Nature 348, 69−73 (1990). | Article | PubMed  | ChemPort |
37. Shioda, T., Levy, J.A. & Cheng-Mayer, C. Macrophage and T cell line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene. Nature 349, 167−169 (1991). | Article | PubMed  | ISI | ChemPort |
38. Hwang, S.S. et al Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1. Science 253, 71−74 (1991). | PubMed  | ISI | ChemPort |
39. Skinner, M.A. et al Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4. J. Virol 62, 4195−4200−(1988). | PubMed  | ISI | ChemPort |
40. Grimaila, R. et al Mutations in the principal neutralizing determinant of human immunodeficiency virus type 1 affect syncytium formation, virus infectivity, growth kinetics, and neutralization. J Virol 66, 1875−1883 (1992). | PubMed  | ISI | ChemPort |
41. Broder, C.C., Nussbaum, O., Gutheil, W.G., Bachovchin, W.W. & Berger, E.A. CD26 antigen and HIV fusion. Science 264, 1156−1159 (1994). | PubMed  | ISI | ChemPort |
42. Patience, C. et al CD26 antigen and HIV fusion. Science 264, 1159−1160 (1994). | PubMed  | ISI | ChemPort |
43. Camerini, D., Planelles, V. & Chen, I.S.Y. CD26 antigen and HIV fusion. Science 264, 1160−1161 (1994). | PubMed  | ISI | ChemPort |
44. Alizon, M. & Dragic, T. CD26 antigen and HIV fusion. Science 264, 1161−1162 (1994). | PubMed  | ISI | ChemPort |
45. Werner, A. et al. CD26 is not required for infection for the lymphoma cell line C8166 with HIV-1. AIDS 8, 1348−1349 (1994). | PubMed  | ISI | ChemPort |
46. West, W.H.L. & Stott, E.J. Cell surface expression of CD26 does not correlate with susceptibility to immunodeficiency viruses. AIDS 8, 1349−1350 (1994). | PubMed  | ISI | ChemPort |
47. Feng, Y., Broder, C.C., Kennedy, P.E. & Berger, E.A. HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272, 872−877 (1996). | PubMed  | ISI | ChemPort |
48. Endres, M.J. et al. CD4-independent infection by HIV-2 is mediated by fusin. Cell 87, 745−756 (1996). | Article | PubMed  | ISI | ChemPort |
49. Federsppiel, B. et al. Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen. Genomics 16, 707−712 (1993). | Article | PubMed  | ISI | ChemPort |
50. Jazin, E.E. et al. A proposed bovine neuropeptide Y (NPY) receptor cDNA clone, or its human homologue, confers neither NPY binding sites nor NPY responsiveness on transfected cells. Regul. Pept 47, 247−258 (1993). | Article | PubMed  | ISI | ChemPort |
51. Loetscher, M. et al. Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. J. Biol Chem. 269, 232−237 (1994). | PubMed  | ISI | ChemPort |
52. Bleul, C.C. et al The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 382, 829−832 (1996). | Article | PubMed  | ISI | ChemPort |
53. Oberlin, E. et al. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 382, 833−835 (1996). | Article | PubMed  | ISI | ChemPort |
54. Bleul, C.C., Fuhlbrigge, R.C., Casanovas, J.M., Aiuti, A. & Springer, T. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J. Exp. Med. 184, 1101−1109 (1996). | Article | PubMed  | ISI | ChemPort |
55. Nagasawa, T. et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 382, 635−638 (1996). | Article | PubMed  | ISI | ChemPort |
56. Samson, M., Labbe, O., Mollereau, C., Vassart, G. & Parmentier, M. Molecular cloning and functional expression of a new human CC-chemokine receptor gene. Biochemistry 35, 3362−3367 (1996). | Article | PubMed  | ISI | ChemPort |
57. Dragic, T. et al. HIV-1 entry into CD4⁺ cells is mediated by the chemokine receptor CD-CKR-5. Nature 381, 667−673 (1996). | Article | PubMed  | ISI | ChemPort |
58. Deng, H. et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 381, 661−667 (1996). | Article | PubMed  | ISI | ChemPort |
59. Alkhatib, G. et al. CC CKR5: A RANTES, MIP-l, MIP-l receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272, 1955−1958 (1996). | PubMed  | ISI | ChemPort |
60. Doranz, B.J. et al. A dual-tropic primary HIV-1 isolate that uses fusin and the -chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 85, 1149−1158 (1996). | Article | PubMed  | ISI | ChemPort |
61. Hyeryun, C. et al. The b-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85, 1135−1148 (1996). | Article | PubMed  | ISI | ChemPort |
62. Combadiere, C., Ahuja, S.K. & Murphy, P.M. Cloning and functional expression of a human eosinophil CC chemokine receptor. J. Biol. Chem. 270, 16491−16494 (1995). (Correction, J. Biol Chem. 270; 30235). | PubMed  | ISI | ChemPort |
63. Berson, J.F. et al. A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains. J. Virol. 70, 6288−6295 (1996). | PubMed  | ISI | ChemPort |
64. Collman, R. et al. An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. J. Virol. 66, 7517−7521 (1992). | PubMed  | ISI | ChemPort |
65. Lapham, C.K. et al. Evidence for cell-surface association between fusin and the CD4-gpl20 complex in human cell lines. Science 274, 602−605 (1996). | Article | PubMed  | ISI | ChemPort |
66. Wu, L. et al CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR5. Nature 384, 179−183 (1996). | Article | PubMed  | ISI | ChemPort |
67. Trkola, A. et al. CD4-dependent, neutralizing antibody-sensitive interactions between HIV-1 gp120 and the CCR-5 CC-chemokine receptor. Nature 384, 184−187 (1996). | Article | PubMed  | ISI | ChemPort |
68. Cocchi, F. et al The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection. Nature Med. 2, 1244−1247 (1996). | Article | PubMed  | ISI | ChemPort |
69. Paxton, W.A. et al. Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposures. Nature Med. 2, 412−417 (1996). | Article | PubMed  | ISI | ChemPort |
70. Liu, R. et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed Individuals to HIV-1 Infection. Cell 86, 367−377 (1996). | Article | PubMed  | ISI | ChemPort |
71. Samson, M. et al. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature. 382, 722−725 (1996). | Article | PubMed  | ISI | ChemPort |
72. Dean, M. et al. Genetic restriction of HIV-1 infection and progression to AIDS by a detection allele of the CKR5 structural gene. Science 273, 1856−1862 (1996). | PubMed  | ISI | ChemPort |
73. Huang, Y. et al. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nature Med. 2, 1240−1243 (1996). | Article | PubMed  | ISI | ChemPort |
74. Rowland-Jones, S. et al. HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women. Nature Med. 1, 59−64 (1995). | Article | PubMed  | ISI |
75. Horuk, R. et al. A receptor for the malarial parasite Plasmodium vivax: The ery-throcyte chemokine receptor. Science 261, 1182−1184 (1993). | PubMed  | ISI | ChemPort |
76. Munoz, A. et al. Long-term survivors with HIV-1 Infection: Incubation period and longitudinal patterns of CD4⁺ lymphocytes. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 8, 496−505 (1994). | ISI |
77. Wild, C., Greenwell, T., Shugars, D., Rimsky-Clarke, L. & Matthews, T. The inhibitory activity of an HIV type 1 peptide correlates with its ability to interact with a leucine zipper structure. AIDS Res. Hum. Retroviruses 11, 323−325 (1995). | PubMed  | ISI | ChemPort |
78. Arenzana-Seisdedos, F. et al. HIV blocked by chemokine antagonist. Nature 383, 400 (1996). | Article | PubMed  | ChemPort |
79. Schmidtmayerova, H., Sherry, B. & Bukrinsky, M. Chemokines and HIV replication. Nature 382, 767 (1996). | Article | PubMed  | ISI | ChemPort |

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