Nature Medicine
2, 1074 - 1075 (1996)
doi:10.1038/nm1096-1074
Immunotherapy for multiple sclerosis: From theory to practiceJack P. Antel, Burkhard Becher
& Trevor OwensDepartment of Neurology and Neurosurgery, Neuroimmunology Unit, McGill University Montreal, Quebec H3A 2B4, Canada T-cell receptor peptide vaccines may hold promise as future therapy for multiple sclerosis (pages 1109−1115).
REFERENCES
- Katz, D. et al. Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis. Ann. Neurol. 34, 661−669 (1993). | PubMed | ISI | ChemPort |
- Talbot, P.J., Paquette, J.S., Ciurli, C., Antel, J.P. & Ouellet, F. Myelin basic protein and human coronavirus 229E cross-reactive T cells in MS. Ann. Neurol. 39, 233−240 (1996). | PubMed | ISI | ChemPort |
- Lehman, P.V., Forsthuber, T., Miller, A. & Sercarz, E.E. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 358, 155−157 (1992). | Article | PubMed | ISI | ChemPort |
- Vandenbark, A.A. Treatment of multiple sclerosis with T-cell receptor peptides: Results of a double-blind pilot trial. Nature Med. 2, 1109−1115 (1996). | Article | PubMed | ISI | ChemPort |
- Ben-Nun, A., Wekerle, H. & Cohen, I.R. Vaccination against autoimmune encephalomyelitis with T-lymphocyte cell lines reactive against myelin basic protein. Nature 292, 60−61 (1981). | PubMed | ChemPort |
- Jerne, N.K. Idiotypic networks and other preconceived ideas. Immunol. Rev. 79, 5−24 (1984). | PubMed | ISI | ChemPort |
- Bell, J.I. & Lathrop, G.M. Multiple loci for multiple sclerosis. Nature Genet. 13, 377−378 (1996). | Article | PubMed | ISI | ChemPort |
- Rudick, R. et al. Clinical outcomes assessment in multiple sclerosis. Ann. Neurol. (in the press).
- Chen, Y., Kuchroo, V.K., Inobe, J., Hafler, D.A. & Weiner, H.L. Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis. Science 265, 1237−1240 (1994). | PubMed | ISI | ChemPort |
- Windhagen, A., Anderson, D.A., Carrizosa, A., Williams, R.E. & Hafler, D.A. IL-12 induces human T cells secreting IL-10 with IFN-
 . J Immunol. 157, 1127−1131 (1996). | PubMed | ISI | ChemPort |
- Brocke, S. et al. Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein. Nature 379, 343−346 (1996). | Article | PubMed | ISI | ChemPort |
|
