Nature Medicine
2, 1071 - 1072 (1996)
doi:10.1038/nm1096-1071
Can a killer be arrested?Felipe KierszenbaumDepartment of Microbiology, Michigan State University, East Lansing, Michigan 48824, USA A promising drug study in a mouse model of chagas' disease raises hopes that a major health and socioeconomic problem can be eliminated.
REFERENCES
- Brener, Z. & Andrade, Z.A. (eds.) Trypanosoma cruzi e Doença de Chagas. 199−248 (Guanabara Koogan, Rio de Janeiro, 1979).
- World Health Organization. Campaign ready to eliminate Chagas from six Latin American countries. TDR News 39, 2 (1992).
- Kierszenbaum, F. chagas' disease, in Vaccination Strategies of Tropical Diseases (ed. Liew, F.-Y.) 173−195 (CRC Press, Boca Raton, Florida, 1989).
- Kierszenbaum, F. & Sztein, M.B. chagas' disease (American trypanosomiasis) in Parasitic Infections and the Immune System. (ed. Kierszenbaum, F.) 53−85 (Academic Press, San Diego, 1994).
- Kierszenbaum, F. Autoimmunity in chagas' disease. J. Parasitol 72, 201−211 (1986). | PubMed | ISI | ChemPort |
- Takle, G.B. & Hudson, L. Autoimmunity in chagas' disease. Curr. Top. Microbiol. Immunol. 145, 79−92 (1989). | PubMed | ISI | ChemPort |
- Kierszenbaum, F. Chagas' disease. in Parasitic Diseases vol. 2 (ed. Mansfield, J.M.) 133−163 (Marcel Dekker, New York, 1984).
- Urbina, J.A. et al. Cure of short-term and long-term experimental chagas' disease using D0870. Science 273, 969−971 (1996). | PubMed | ISI | ChemPort |
- Lazardi, K., Urbina, J.A. & de Souza, W. Ultra-structural alterations induced by ICI 195,739, a bis-triazol derivative with strong anti-proliferative action against Trypanosoma (Schizotrypanum) cruzi. Antimicrob. Agents Chemother. 35, 736−740 (1991). | ChemPort |
- Urbina, J.A., Lazardi, K., Aguirre, T., Piras, M.M. & Piras, R. Antiproliferative effects and mechanism of action of ICI 195,739, a novel bis-triazol derivative, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi. Antimicrob. Agents Chemother 35, 730−735 (1991). | ChemPort |
|
