Nature Medicine
2, 27 - 29 (1996)
doi:10.1038/nm0196-27
Deaf and dizzy mice with mutated myosin motorsPeter G. GillespieDepartments of Physiology and Neuroscience, The Johns Hopkins University Baltimore, Maryland 21205, USA Yet another mouse deafness gene encodes an unconventional myosin isozyme.
REFERENCES
- Avraham, K.B. et al. The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. Nature Genet. 11, 369−375 (1995). | PubMed | ISI | ChemPort |
- Markin, V.S. & Hudspeth, A.J. Gating-spring models of mechanoelectrical transduction by hair cells of the internal ear. Annu. Rev. Biophys. Biomol. Struct. 24, 59−83 (1995). | Article | PubMed | ISI | ChemPort |
- Lyon, M.F. & Searle, A.G. Genetic Variants and Strains of the Laboratory Mouse (Oxford University Press, Oxford, 1989).
- Gibson, F. et al. A type VII myosin encoded by the mouse deafness gene shaker 1. Nature 374, 62−64 (1995). | Article | PubMed | ISI | ChemPort |
- Weil, D. et al. Defective myosin VIIA gene responsible for Usher syndrome type 1B. Nature 374, 60−61 (1995). | Article | PubMed | ISI | ChemPort |
- Deol, M.S. & Green, M.C. Snell's waltzer, a new mutation affecting behavior and the inner ear in the mouse. Genet. Res. 8, 339−345 (1966). | PubMed | ISI | ChemPort |
- Sole, C.K., Derfler, B.H., Duyk, G.M. & Corey, D.P. Molecular cloning of myosins from bullfrog saccular macula: A candidate for the hair Cell adaptation motor. Auditory Neurosci. 1, 63−75 (1994).
- Hasson, T. & Mooseker, M.S. Porcine myosin-VI: Characterization of a new mammalian unconventional myosin. J. Cell Biol. 127, 425−440 (1994). | Article | PubMed | ISI | ChemPort |
- Hasson, T. et al. Expression in cochlea and retina of myosin Vila, the gene product defective in Usher syndrome type 1B. Proc. Natl. Acad. Sci. USA 92, 9815−9819 (1995). | PubMed | ChemPort |
- Tilney, L.G., Tllney, M.S. & DeRosier, D.J. Actin filaments, stereocilia, and hair cells: How cells count and measure. Annu. Rev. Cell Biol. 8, 257−274 (1992). | Article | PubMed | ISI | ChemPort |
- Gillespie, P.G., Wagner, M.C. & Hudspeth, A.J. Identification of a 120-kD hair-bundle myosin I located near stereociliary tips. Neuron 11, 581−594 (1993). | Article | PubMed | ISI | ChemPort |
- Metcalf, A.B., Chelliah, Y. & Hudspeth, A.J. Molecular cloning of a myosin I
 isozyme that may mediate adaptation by hair cells of the bullfrog's internal ear. Proc. Natl. Acad. Sci. USA 91, 11821−11825 (1994). | PubMed | ChemPort |
- Eatock, R.A., Corey, D.P. & Hudspeth, A.J. Adaptation of mechanoelectrical transduction in hair cells of the bullfrog�?Ts sacculus. J. Neurosci. 7, 2821−2836 (1987). | PubMed | ISI | ChemPort |
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