Malaria remains the most deadly human parasitic disease. A new study finds that malaria parasites signal to mast cells to promote disease through the expansion of specialist dendritic cells and the subsequent activation of pathogenic CD8+ T cells (pages 730–738).
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Engwerda, C., Kumar, R. Mast cells fuel the fire of malaria immunopathology. Nat Med 19, 672–674 (2013). https://doi.org/10.1038/nm.3227
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DOI: https://doi.org/10.1038/nm.3227
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