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Shifting HIFs in osteoarthritis

A Corrigendum to this article was published on 01 July 2010

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There is no cure for osteoarthritis—the most common disease of the joints. By piecing together the molecular events that drive the progression of this debilitating disease, recent studies published in Nature Medicine put hypoxia-inducible factor-2α (HIF-2α) in the driver's seat, opening up new avenues for early detection and treatment (pages 678–686 and 687–693).

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Figure 1: HIF-1α and HIF-2α have different functions in the cartilage.

Kimberly Caesar

Change history

  • 07 July 2010

     In the version of this article initially published online, a reference was missing and a label was misplaced within the figure. The errors have been corrected for the PDF and HTML versions of this article.

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Acknowledgements

Supported by the VA Research Service and US National Institutes of Health grants PAGO7996, AR1067966, 5T32AR007608.

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Correspondence to Robert Terkeltaub.

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Husa, M., Liu-Bryan, R. & Terkeltaub, R. Shifting HIFs in osteoarthritis. Nat Med 16, 641–644 (2010). https://doi.org/10.1038/nm0610-641

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