Between Bedside and Bench

Nature Medicine 15, 999 - 1001 (2009)

A safer stem cell: on guard against cancer

Rahul Jandial1,2 & Evan Y Snyder1

Before stem cell therapies become mainstream, several hurdles must be overcome. One challenge is developing air-tight approaches to assure that stem cell transplantation does not give rise to tumors. Another is finding safe ways to induce pluripotency in adult stem cells, which can then be used for transplantation. In Bedside to Bench, Evan Snyder and Rahul Jandial discuss the risks of tumorigenesis in stem cell therapies, and, in Bench to Bedside, Laura Clarke and Derek van der Kooy examine new ways to induce pluripotency.

  1. Rahul Jandial and Evan Y. Snyder are at the Burnham Institute for Medical Research, La Jolla, California, USA.
  2. Rahul Jandial is also affiliated with the Division of Neurosurgery, City of Hope, Duarte, California, USA.

Correspondence to: Evan Y Snyder1 e-mail:


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