1. Aleix Prat and Charles M. Perou are at the Lineberger Comprehensive Cancer Center, Departments of Genetics and Pathology & Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Correspondence to: Charles M. Perou¹ e-mail: cperou@med.unc.edu

Abstract

Mammary epithelial cell development is thought to progress from undifferentiated stem cells into at least two differentiated cell types. A new study has now characterized some of these distinct developmental stages and links them to tumor subtypes previously defined by gene expression profiling (pages 907–913).

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