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Nature Medicine 15, 732–733 (1 July 2009) | doi:10.1038/nm0709-732

Targeting lymphotoxin depletes pathogenic T cells

Anna M. Hansen & Rachel R. Caspi

Over the last ten years, the treatment options for individuals with autoimmune disorders have improved dramatically. A range of protein-based therapeutic agents have entered the market that specifically target the signaling pathways that cause conditions such as rheumatoid arthritis and multiple sclerosis.