1. The Mount Sinai Bone Program, Mount Sinai School of Medicine, New York, New York, USA.

Correspondence to: Mone Zaidi¹ e-mail: mone.zaidi@mssm.edu

Abstract

To maintain skeletal integrity and prevent fractures, degradation and rebuilding of bone must occur in synchrony. Transforming growth factor-1 is now found to coordinate this restructuring process: the molecule is released during bone degradation and stimulates bone rebuilding (pages 757–765).

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