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Nature Medicine 15, 612–613 (1 June 2009) | doi:10.1038/nm0609-612
IFN-|[alpha]| wakes up sleeping hematopoietic stem cells
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Abstract
At homeostasis, complex regulatory networks maintain the ongoing production of all blood cell types. During this process, very few hematopoietic stem cells (HSCs) actively divide, and most of them remain quiescent in the bone marrow.
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