About the cover
June 2009 Volume 15 No 6
Reduced levels of gastric acid results in poor calcium absorption from the diet and defects in bone
homeostasis. On p 674 of this issue, Michael Amling and his colleagues show that deficiency in an ion pump subunit resulting in high gastric pH and poor osteoclast activity leads to osteopetrosis and rickets. The cover image is of multinucleated osteoclasts destroying bone in a non-decalcified
section of human bone. The image is pseudocolored, with mineralized bone appearing orange. Photo: Michael Amling, Hamburg.
