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Nature Medicine 15, 612 - 613 (2009)
doi:10.1038/nm0609-612

IFN-alpha wakes up sleeping hematopoietic stem cells

Emmanuelle Passegué1 & Patricia Ernst2

  1. Emmanuelle Passegué is at the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Department of Medicine, Division of Hematology/Oncology, University of California–San Francisco, San Francisco, California, USA
  2. Patricia Ernst is at the Dartmouth Medical School, Department of Genetics and Norris Cotton Cancer Center, Hanover, New Hampshire, USA.
    e-mail: Passeguee@stemcell.ucsf.edu or e-mail: patricia.ernst@dartmouth.edu


The cytokine interferon-alpha stimulates the turnover and proliferation of hematopoietic cells in vivo (pages 696–700). The findings hint at a new strategy to treat hematopoietic cancers.

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